protein

Recombinant human MTPN protein

ATGP0621

20 ug

80 USD

Recombinant human MTPN protein

1-118aa

ATGP0621

NP_665807

MTPN (myotrophin), an ankyrin repeat protein, is stimulates protein synthesis and cardiomyocyte growth to initiate cardiac hypertrophy by activating the NF-kappaB signaling cascade. This protein plays a potential role in cerebellar morphogenesis and may function in differentiation of cerebellar neurons, particularly of granule cells. Elevated levels of MTPN are expressed in human dilated cardiomyopathic and ischemic hearts. Recombinant human MTPN, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Myotrophin, Protein V-1, GCDP, Myotrophin, Protein V 1, Protein V1,

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Sen S., et al. (2008) J Biol Chem. 283(41):27947-56.;; Sivasubramanian N., et al (2002) J Biol Chem. 277(26):23888-97.;;

> 90% by SDS-PAGE

SDS-PAGE

Human

Neuroscience

15 kDa (138aa) confirmed by MALDI-TOF

MCDKEFMWAL KNGDLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPDGLTAFEATDN QAIKALLQ

His-Tag

E.coli

Recombinant Protein

P58546

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