protein

Recombinant mouse alpha-Synuclein protein

ATGP0619

20 ug

80 USD

Recombinant mouse alpha-Synuclein protein

1-140aa

ATGP0619

NP_033247

Alpha-Synuclein, also known as SNCA, an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-Synuclein has been suggested to be implicated in the pathogenesis of Parkinson. Recombinant mouse alpha-Synuclein, was expressed in E. coli and purified by using conventional chromatography techniques

alpha-Synuclein, Snca, Syn, alpha-Synuclein, NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor

1mg/ml (determined by BCA assay)

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing, 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

ueda K., et al. (1993) Proc. Natl. Acad. Sci. uSA 90:11282-11286 ;; Kim J., et al. (1997) Molecules and Cells 7:78-83 ;; Jakes R., et al. (1994) FEBS lett. 345:27-32. ;;

> 95% by SDS-PAGE

SDS-PAGE

Mouse

Neuroscience

14.4 kDa (140aa) confirmed by MALDI-TOF

MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP GSEAYEMPSE EGYQDYEPEA

Non-Tagged

E.coli

Recombinant Protein

O55042

a-Synuclein, alpha-Synuclein, Snca, Syn, alpha-Synuclein, NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor,ATGP0619-10ug,ATGP0619-20ug,ATGP0619-50ug,ATGP0619-100ug,ATGP0619-250ug,ATGP0619-500ug,ATGP0619-1mg,ATGP0619-10,ATGP0619-20,ATGP0619-50,ATGP0619-100,ATGP0619-250,ATGP0619-500,ATGP0619-1

Kim S, et al. Alpha-synuclein induces migration of BV-2 microglial cells by up-regulation of CD44 and MT1-MMP. (J Neurochem. 2009){https://pubmed.ncbi.nlm.nih.gov/19457162/};;Joo SH, et al. Regulation of matrix metalloproteinase-9 and tissue plasminogen activator activity by alpha-synuclein in rat primary glial cells. (Neurosci Lett. 2010){https://pubmed.ncbi.nlm.nih.gov/20026244/};;Lee HJ, et al. Enzyme-linked immunosorbent assays for α-synuclein with species and multimeric state specificities. (J Neurosci Methods. 2011){https://pubmed.ncbi.nlm.nih.gov/21658411/};;Park HJ, et al. Mesenchymal stem cells enhance α-synuclein clearance via M2 microglia polarization in experimental and human parkinsonian disorder. (Acta Neuropathol. 2016){https://pubmed.ncbi.nlm.nih.gov/27497943/}