Recombinant human UROD protein | NKMAX ATGP0612 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human UROD protein

catalog :

ATGP0612

quantity :

20 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human UROD protein

Domain :

1-367aa

Catalog number (SKU) :

ATGP0612

NCBI :

AAH01778

Description :

UROD is the fifth enzyme in the human heme biosynthetic pathway and is responsible for the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are responsible for three autosomal disorders in humans: familial porphyria cutanea tarda (f-PCT), sporadic porphyria cutanea tarda (s-PCT) and hepatoerythropoietic porphyria (HEP). Recombinant human UROD protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

uroporphyrinogen decarboxylase, PCT, uroporphyrinogen decarboxylase, uPD, uRO D, uRO-D

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 1mM DTT, 0.1M NaCl, and 1mM EDTA

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Lewis CA Jr., et al. (2008) Proc Natl Acad Sci u S A. 105(45):17328-33. ;; Garey JR., et al. (1989) Blood. 73(4):892-5. ;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Enzymes & Proteases

Molecular Weight :

43.0 kDa (387aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MEANGLGPQG FPELKNDTFL RAAWGEETDY TPVWCMRQAG RYLPEFRETR AAQDFFSTCR SPEACCELTL QPLRRFPLDA AIIFSDILVV PQALGMEVTM VPGKGPSFPE PLREEQDLER LRDPEVVASE LGYVFQAITL TRQRLAGRVP LIGFAGAPWT LMTYMVEGGG SSTMAQAKRW LYQRPQASHQ LLRILTDALV PYLVGQVVAG AQALQLFESH AGHLGPQLFN KFALPYIRDV AKQVKARLRE AGLAPVPMII FAKDGHFALE ELAQAGYEVV GLDWTVAPKK ARECVGKTVT LQVNLDPCAL YASEEEIGQL VKQMLDDFGP HRYIANLGHG LYPDMDPEHV GAFVDAVHKH SRLLRQN

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P06132

Internal Search Terms :

uROD, uroporphyrinogen decarboxylase, PCT, uroporphyrinogen decarboxylase, uPD, uRO D, uRO-D,ATGP0612-10ug,ATGP0612-20ug,ATGP0612-50ug,ATGP0612-100ug,ATGP0612-250ug,ATGP0612-500ug,ATGP0612-1mg,ATGP0612-10,ATGP0612-20,ATGP0612-50,ATGP0612-100,ATGP0612-250,ATGP0612-500,ATGP0612-1

more info or order :

NKMAX product webpage