Recombinant human K-Ras protein | NKMAX ATGP0609 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human K-Ras protein

catalog :

ATGP0609

quantity :

20 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human K-Ras protein

Domain :

1-185aa (partial)

Catalog number (SKU) :

ATGP0609

NCBI :

AAH13572.1

Description :

KRAS is a member of the small GTPase superfamily. This protein is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. under normal conditions, Ras family members influence cell growth and differentiation events in a subcellular membrane compartmentalization-based signaling system. Oncogenic Ras can deregulate processes that control both cell proliferation and apoptosis. Recombinant human KRAS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

GTPase Kras, KRAS proto-oncogene GTPase, KRAS2, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, Kirsten rat sarcoma viral oncogene homolog, KRAS1, K-Ras4B, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, RASK2

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl,1mM DTT, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Lee W., et al. (2010) Nature. 465(7297):473-7.;; Singh M., et al. (2010) Nat Biotechnol. 28(6):585-93;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

23.2 kDa (205aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG HEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK SKTKC

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P01116

Internal Search Terms :

K-RAS, GTPase Kras, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, NS3, RASK2, GTPase Kras,K-RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS 1, NS 3,ATGP0609-10ug,ATGP0609-20ug,ATGP0609-50ug,ATGP0609-100ug,ATGP0609-250ug,ATGP0609-500ug,ATGP0609-1mg,ATGP0609-10,ATGP0609-20,ATGP0609-50,ATGP0609-100,ATGP0609-250,ATGP0609-500,ATGP0609-1

more info or order :

NKMAX product webpage