Recombinant human FKBP22/FKBP14 protein | NKMAX ATGP0604 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human FKBP22/FKBP14 protein

catalog :

ATGP0604

quantity :

20 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human FKBP22/FKBP14 protein

Domain :

20-211aa

Catalog number (SKU) :

ATGP0604

NCBI :

NP_060416

Description :

FKBP14, also known as 22 kDa FK506-binding protein, is an enzyme that accelerates the folding of proteins during protein synthesis. This protein contains two EF-hand domains and one PPIase FKBP-type domain. Truncation of the amino-terminus of FKBP14 greatly reduces peptidyl prolyl cis-trans isomerase activity, therefore suggesting that the PPIase FKBP-type domain must be located at the N-terminus. Recombinant human FKBP14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography

Alternative Names :

22 kDa FK506 binding protein, FK506 binding protein 14 (22 kDa), FKBP22, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP14, PPIase, Rotamase

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Tremmel D., et al. (2007) J Mol Biol. 369(1):55-68.;; Budiman C., et al. (2009) FEBS J. 276(15):4091-101.;;

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 240nmol/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAPF-pNA per minute at 37C in Tris-Hcl pH8.0 using chymotrypsin.

Applications :

SDS-PAGE, Enzyme Activity

Antigen Species :

Human

Gene Category :

Heat Shock Proteins

Molecular Weight :

24.2 kDa (213aa) confirmed by MALDI-TOF

Bioactivity Comment and Pics :

Specific activity is > 240 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAPF-pNA per minute at 37C in Tris-Hcl pH8.0 using chymotrypsin.

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MALIPEPEVK IEVLQKPFIC HRKTKGGDLM LVHYEGYLEK DGSLFHSTHK HNNGQPIWFT LGILEALKGW DQGLKGMCVG EKRKLIIPPA LGYGKEGKGK IPPESTLIFN IDLLEIRNGP RSHESFQEMD LNDDWKLSKD EVKAYLKKEF EKHGAVVNES HHDALVEDIF DKEDEDKDGF ISAREFTYKH DEL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9NWM8

Internal Search Terms :

22 kDa FK506 binding protein, FK506 binding protein 14, FK506 binding protein 14 (22 kDa), FKBP 22, FKBP22, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP14, PPIase, Rotamase, FKBP14, FKBP 14, ATGP0604-10ug, ATGP0604-20ug, ATGP0604-50ug, ATGP0604-100ug, ATGP0604-250ug, ATGP0604-500ug, ATGP0604-1mg, ATGP0604-010, ATGP0604-020, ATGP0604-050, ATGP0604-100, ATGP0604-250, ATGP0604-500, ATGP0604-01M

more info or order :

NKMAX product webpage