Recombinant human Transgelin/TAGLN protein | NKMAX ATGP0602 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Transgelin/TAGLN protein

catalog :

ATGP0602

quantity :

20 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Transgelin/TAGLN protein

Domain :

1-201aa

Catalog number (SKU) :

ATGP0602

NCBI :

NP_001001522

Description :

TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein that belongs to the calponin family. This protein is expressed abundantly in fibroblasts and smooth muscle. It is involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. During embryogenesis, TAGLN is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. It is downregulated in several transformed cell lines, indicating that a reduction of TAGLN expression may be an early indicator of the onset of transformation. Recombinant human TAGLN protein, fused to his-tag at N-terminus was expressed in E. coli and purified by using conventional chromatography techniques

Alternative Names :

WS3-10, Transgelin, TAGLN1, Smooth muscle protein 22-alpha, SMCC, SM22 alpha, SM22

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kobayashi R., et al. (1994) Biochem Biophys Res Commun. 198(3):1275-80. ;; Thweatt R., et al. (1992) Biochem Biophys Res Commun. 187(1):1-7. ;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cytoskeleton

Molecular Weight :

24.8 kDa (221aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MANKGPSYGM SREVQSKIEK KYDEELEERL VEWIIVQCGP DVGRPDRGRL GFQVWLKNGV ILSKLVNSLY PDGSKPVKVP ENPPSMVFKQ MEQVAQFLKA AEDYGVIKTD MFQTVDLFEG KDMAAVQRTL MALGSLAVTK NDGHYRGDPN WFMKKAQEHK REFTESQLQE GKHVIGLQMG SNRGASQAGM TGYGRPRQII S

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q01995

Internal Search Terms :

SM 22, SM22, SM22 alpha, SM22-alpha, SMCC, Smooth muscle protein 22 alpha, Smooth muscle protein 22-alpha, TAGLN, TAGLN 1, TAGLN1, TAGLN-1, Transgelin, WS3 10, WS310, WS3-10, ATGP0602-10ug, ATGP0602-20ug, ATGP0602-50ug, ATGP0602-100ug, ATGP0602-250ug, ATGP0602-500ug, ATGP0602-1mg, ATGP0602-010, ATGP0602-020, ATGP0602-050, ATGP0602-100, ATGP0602-250, ATGP0602-500, ATGP0602-01M

more info or order :

NKMAX product webpage