Recombinant human RUNX3/CBFA3 protein | NKMAX ATGP0576 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RUNX3/CBFA3 protein

catalog :

ATGP0576

quantity :

10 ug

price :

99 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RUNX3/CBFA3 protein

Domain :

53-186aa

Catalog number (SKU) :

ATGP0576

NCBI :

NP_004341

Description :

RuNX3, also known as runt-related transcription factor 3, belongs to the RuNX family that regulate the expression of genes involved in cellular differentiation and cell cycle progression. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It is a strong candidate as a gastric cancer tumor suppressor. Recombinant human RuNX3, fused to His-tag at N-terminus, protein was expressed in E. coli and purified by using conventional chromatography techniques

Alternative Names :

Runt-related transcription factor 3, AML2, CBFA3, PEBP2aC, Runt-related transcription factor 3 Acute myeloid leukemia 2 protein, Acute myeloid leukemia gene 2, AML 2, CBF alpha 3, CBFA 3, Core binding factor alpha 3 subunit, core binding factor, Core binding factor runt domain alpha subunit 3, Core binding factor subunit alpha 3.M574, core-binding factor, FLJ34510, MGC16070, Oncogene AML 2, PEA2 alpha C, PEBP2 alpha C, Pebp2a3, Polyomavirus enhancer binding protein 2 alpha C subunit, runt domain alpha subunit 3, runt related transcription factor 3, RuNX 3, SL3 3 enhancer factor 1 alpha C subunit, SL3/AKV core binding factor alpha C subunit, Transcription factor AML2.

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Vogiatzi P. et al. (2006) Cancer Biol Ther. 5(4):371-4.;; Li QL,et al. (2002)Cell. 109(1):113-24.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

17.1 kDa (155aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MRSMVDVLAD HAGELVRTDS PNFLCSVLPS HWRCNKTLPV AFKVVALGDV PDGTVVTVMA GNDENYSAEL RNASAVMKNQ VARFNDLRFV GRSGRGKSFT LTITVFTNPT QVATYHRAIK VTVDGPREPR RHRQK

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q13761

Internal Search Terms :

RUNX3, CBFA3, Runt-related transcription factor 3, AML2, CBFA3, PEBP2aC, Runt-related transcription factor 3 Acute myeloid leukemia 2 protein, Acute myeloid leukemia gene 2, AML 2, CBF alpha 3, CBFA 3, Core binding factor alpha 3 subunit, core binding factor, Core binding factor runt domain alpha subunit 3, Core binding factor subunit alpha 3.M574, core-binding factor, FLJ34510, MGC16070, Oncogene AML 2, PEA2 alpha C, PEBP2 alpha C, Pebp2a3, Polyomavirus enhancer binding protein 2 alpha C subunit, runt domain alpha subunit 3, runt related transcription factor 3, RuNX 3, SL3 3 enhancer factor 1 alpha C subunit, SL3/AKV core binding factor alpha C subunit, Transcription factor AML2.,ATGP0576-10ug,ATGP0576-20ug,ATGP0576-50ug,ATGP0576-100ug,ATGP0576-250ug,ATGP0576-500ug,ATGP0576-1mg,ATGP0576-10,ATGP0576-20,ATGP0576-50,ATGP0576-100,ATGP0576-250,ATGP0576-500,ATGP0576-1

more info or order :

NKMAX product webpage