Recombinant human SUB1 protein | NKMAX ATGP0573 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human SUB1 protein

catalog :

ATGP0573

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human SUB1 protein

Domain :

1-127aa

Catalog number (SKU) :

ATGP0573

NCBI :

NP_006704.3

Description :

SuB1, also known as PC4, is a general coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. SuB1 interacts with the activation domain of transcription factor IIA (TFIIA) and TATA-binding protein (TBP) -associated factors (TAFs) to directly bind to double stranded DNA. This protein induces both activation and repression of RNAPII basal transcription, depending on the presence or absence of these transcription factors and holoenzyme components. Recombinant human SuB1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

SUB1 regulator of transcriptio, SUB1 homolog transcriptional regulator, Activated RNA polymerase II transcriptional coactivator p15, Positive cofactor 4, PC4, SUB1 homolog, p14, PC4, RPO2TC1

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Tavenet A., et al. (2009) Proc Natl Acad Sci u S A. 106(34):14265-70. ;; Scott KL., et al. (2009) Nature. 459(7250):1085-90.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

16.5 kDa (147aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MPKSKELVSS SSSGSDSDSE VDKKLKRKKQ VAPEKPVKKQ KTGETSRALS SSKQSSSSRD DNMFQIGKMR YVSVRDFKGK VLIDIREYWM DPEGEMKPGR KGISLNPEQW SQLKEQISDI DDAVRKL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P53999

Internal Search Terms :

SuB1, Activated RNA polymerase II transcriptional coactivator p15, p14, P15, PC4, Activated RNA polymerase II transcriptional coactivator p15 Activated RNA polymerase II transcriptional coactivator p15, Interferon related developmental regulator 1, MGC102747, PC4 LSB, Positive cofactor 4, RPO2TC1, SuB1, SuB1 homolog.,ATGP0573-10ug,ATGP0573-20ug,ATGP0573-50ug,ATGP0573-100ug,ATGP0573-250ug,ATGP0573-500ug,ATGP0573-1mg,ATGP0573-10,ATGP0573-20,ATGP0573-50,ATGP0573-100,ATGP0573-250,ATGP0573-500,ATGP0573-1

more info or order :

NKMAX product webpage