protein

Recombinant human S100P protein

ATGP0565

20 ug

70 USD

Recombinant human S100P protein

1-95aa

ATGP0565

NP_005971.1

S100P is a Ca2+ binding protein that belongs to S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100P is involved in diverse biological functions but the exact role or mechanism of its action is still largely unknown. upon binding of calcium ions S100P undergoes a conformational change that results in an exposure of a hydrophobic surface which allows the interaction with specific target proteins. Recombinant human S100P protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

S100 calcium binding protein P, S100E, S100 calcium binding protein P MIG9, Migration inducing gene 9, Protein S100P, S100 calcium binding protein P, S100 P.

1mg/ml (determined by BCA assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 50mM NaCl

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Dowen S.E., et al (2005) Am. J. Pathol. 166:81-92;; Koltzscher M, et al (2003) Mol Biol Cell. 14(6):2372-84;;

> 90% by SDS-PAGE

SDS-PAGE

Human

Cancer

12.6 kDa (115aa) confirmed by MALDI-TOF

MTELETAMGM IIDVFSRYSG SEGSTQTLTK GELKVLMEKE LPGFLQSGKD KDAVDKLLKD LDANGDAQVD FSEFIVFVAA ITSACHKYFE KAGLK

His-Tag

E.coli

Recombinant Protein

P25815

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Chiba M, et al. Novel quantitative analysis of the S100P protein combined with endoscopic ultrasound-guided fine needle aspiration cytology in the diagnosis of pancreatic adenocarcinoma. (Oncol Rep. 2017){https://pubmed.ncbi.nlm.nih.gov/28260012/}