Recombinant human FKBP36/FKBP6 protein | NKMAX ATGP0560 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human FKBP36/FKBP6 protein

catalog :

ATGP0560

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human FKBP36/FKBP6 protein

Domain :

1-327aa

Catalog number (SKU) :

ATGP0560

NCBI :

NP_003593.3

Description :

FK506 binding protein 6, also known as FKBP6, is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. ubiquitously expressed in all tissues, FKBP6 is present at highest levels in testis, liver, kidney, skeletal muscle and heart. Deletion of FKBP6 may contribute to hypercalcemia and growth delay in Williams-Beuren syndrome. Recombinant human FKBP6, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Inactive peptidyl-prolyl cis-trans isomerase FKBP6, Inactive PPIase FKBP6, 36 kDa FK506-binding protein, 36 kDa FKBP, FKBP-36, FK506-binding protein 6, FKBP-6, Immunophilin FKBP36, peptidylprolyl cis-trans isomerase, Rotamase

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 1mM EDTA, 0.2M NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Crackower MA., et al. (2003) Science. 300(5623):1231-5.;; Metcalfe K., et al. (2005) Clin Dysmorphpl. 14(2): 61-5.;;

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 190nmol/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAPF-pNA per minute at 25C in Tris-Hcl pH8.0 using chymotrypsin.

Applications :

SDS-PAGE, Enzyme Activity

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

39.3 kDa (347aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Specific activity is > 190 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAPF-pNA per minute at 25C in Tris-Hcl pH8.0 using chymotrypsin.

Amino Acid Sequence :

MGGSALNQGV LEGDDAPGQS LYERLSQRML DISGDRGVLK DVIREGAGDL VAPDASVLVK YSGYLEHMDR PFDSNYFRKT PRLMKLGEDI TLWGMELGLL SMRRGELARF LFKPNYAYGT LGCPPLIPPN TTVLFEIELL DFLDCAESDK FCALSAEQQD QFPLQKVLKV AATEREFGNY LFRQNRFYDA KVRYKRALLL LRRRSAPPEE QHLVEAAKLP VLLNLSFTYL KLDRPTIALC YGEQALIIDQ KNAKALFRCG QACLLLTEYQ KARDFLVRAQ KEQPFNHDIN NELKKLASCY RDYVDKEKEM WHRMFAPCGD GSTAGES

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O75344

Internal Search Terms :

FKBP6, FK506 binding protein 6 36kDa, FKBP36, PPIase FKBP6, FK506 binding protein 6, 36kDa 36 kDa FK506 binding protein, EC 5.2.1.8, FK506 binding protein 6, FKBP 36, Immunophilin FKBP36, Peptidyl prolyl cis trans isomerase, PPIase, Rotamase.,ATGP0560-10ug,ATGP0560-20ug,ATGP0560-50ug,ATGP0560-100ug,ATGP0560-250ug,ATGP0560-500ug,ATGP0560-1mg,ATGP0560-10,ATGP0560-20,ATGP0560-50,ATGP0560-100,ATGP0560-250,ATGP0560-500,ATGP0560-1

more info or order :

NKMAX product webpage