Recombinant human RAB27A protein | NKMAX ATGP0556 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RAB27A protein

catalog :

ATGP0556

quantity :

20 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RAB27A protein

Domain :

1-221aa

Catalog number (SKU) :

ATGP0556

NCBI :

NP_899059

Description :

Ras-related protein Rab-27A, also known as RAB27A, belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Also, RAB27A regulates the cytotoxic granule exocytosis and affect T-lymphocyte and macrophage-activation. It is widely expressed with significant expression in pancreatic islets and pituitary tissue, and low expression in brain. Defects in RAB27A cause Griscelli syndrome type 2 (GS2). Recombinant human RAB27A, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Ras-related protein Rab-27A, GS2, RAM, RAB27, Ras-related protein Rab-27A GTP-binding protein Ram, HsT18676.MGC117246, Rab-27, RAB27A, member RAS oncogene family, Ras-related protein Rab27A.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kuroda TS., et al. (2002) J Biol Chem. 277(11):9212-8.;; Barral DC., et al. (2002) J Clin Invest. 110:61-5.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

27 kDa (241aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MSDGDYDYLI KFLALGDSGV GKTSVLYQYT DGKFNSKFIT TVGIDFREKR VVYRASGPDG ATGRGQRIHL QLWDTAGQER FRSLTTAFFR DAMGFLLLFD LTNEQSFLNV RNWISQLQMH AYCENPDIVL CGNKSDLEDQ RVVKEEEAIA LAEKYGIPYF ETSAANGTNI SQAIEMLLDL IMKRMERCVD KSWIPEGVVR SNGHASTDQL SEEKEKGACG C

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P51159

Internal Search Terms :

Rab27a, Ras-related protein Rab-27A, GS2, RAM, RAB27, Ras-related protein Rab-27A GTP-binding protein Ram, HsT18676.MGC117246, Rab-27, RAB27A, member RAS oncogene family, Ras-related protein Rab27A.,ATGP0556-10ug,ATGP0556-20ug,ATGP0556-50ug,ATGP0556-100ug,ATGP0556-250ug,ATGP0556-500ug,ATGP0556-1mg,ATGP0556-10,ATGP0556-20,ATGP0556-50,ATGP0556-100,ATGP0556-250,ATGP0556-500,ATGP0556-1

more info or order :

NKMAX product webpage