protein

Recombinant human S100A9 protein

ATGP0543

20 ug

70 USD

Recombinant human S100A9 protein

1-114aa

ATGP0543

NP_002956.1

S100-A9, also known as Calgranulin B, belongs to the S100 family containing EF-hand type Ca2+-binding proteins. It is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation, and associated with the disease cystic fibrosis. S100A9 has been implicated in the abnormal differentiation of myeloid cells in the stroma of cancer. This protein may function in the inhibition of casein kinase. Recombinant S100A9 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Protein S100-A9, Calgranulin B, 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14, Protein S100-A9 AI323541, B8Ag, BEE11, CAGA, Calgranulin-A, Calprotectin L1L subunit, Calprotectin, included, CGLA, Chemotactic cytokine CP-10, CP-10, Cystic fibrosis antigen, Leukocyte L1 complex light chain MA387, MIF, Migration inhibitory factor-related protein 8, Myeloid-related protein 8, Neutrophil cytosolic 7 kDa protein, NIF, p8, Pro-inflammatory S100 cytokine, Protein S100-A8, S100 calcium binding protein A8, S100 calcium binding protein A8 (calgranulin A), S100A8, S100A8/S100A9 complex, included, urinary stone protein band A.

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Schafer BW. et al. (1996) Trends Biochem Sci. 21(4):134-40.;; Nacken W,.et al. (2003) Microsc Res Tech. 60(6):569-80.;;

> 90% by SDS-PAGE

SDS-PAGE

Human

Cancer

14.3 kDa (122aa) confirmed by MALDI-TOF

MTCKMSQLER NIETIINTFH QYSVKLGHPD TLNQGEFKEL VRKDLQNFLK KENKNEKVIE HIMEDLDTNA DKQLSFEEFI MLMARLTWAS HEKMHEGDEG PGHHHKPGLG EGTP

His-Tag

E.coli

Recombinant Protein

P06702

S100A9,ATGP0543-10ug,ATGP0543-20ug,ATGP0543-50ug,ATGP0543-100ug,ATGP0543-250ug,ATGP0543-500ug,ATGP0543-1mg,ATGP0543-10,ATGP0543-20,ATGP0543-50,ATGP0543-100,ATGP0543-250,ATGP0543-500,ATGP0543-1

Kwon CH, et al. S100A8 and S100A9 Promotes Invasion and Migration through p38 Mitogen-Activated Protein kinase-Dependent NF-kB Activation in Gastric Cancer Cells. (Mol Cells. 2013){https://pubmed.ncbi.nlm.nih.gov/23456298/};;Nishikawa Y, et al. Calprotectin Induces IL-6 and MCP-1 Production via Toll-Like Receptor 4 Signaling in Human Gingival Fibroblasts. (J Cell Physiol. 2017){https://pubmed.ncbi.nlm.nih.gov/27925202/};;Suzuki S, et al. CD147 expression correlates with lymph node metastasis in T1-T2 squamous cell carcinoma of the tongue. (Oncol Lett. 2017){https://pubmed.ncbi.nlm.nih.gov/29085466/};;{}