product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Profilin 2/PFN2 protein
catalog :
ATGP0535
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Profilin 2/PFN2 protein
Domain :
1-140aa
Catalog number (SKU) :
ATGP0535
NCBI :
AAH18049
Description :
PFN2 is a ubiquitous actin monomer-binding protein belonging to the profilin family. This protein is ubiquitously expressed with highest expression in kidney, brain and skeletal muscle. Like other members of the profilin family, PFN2 functions as an actin monomer-binding protein that influences the structure of the cytoskeleton by regulating actin polymerization in response to extracellular signals. At high concentrations, it prevents the polymerization of actin whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Recombinant PFN2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Profilin 2, PFL, Profilin 2 D3S1319E, PFN 2, PFN2, Profilin II, ProfilinII, Profilin2
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Gieslmann R., et al. (1995) Eur J Bilchem. 229(3):621-8. ;; Reinhard M., et al. (1995) EMBO J. 14(8):1583-9. ;;
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cytoskeleton
Molecular Weight :
17.2 kDa (160aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MAGWQSYVDN LMCDGCCQEA AIVGYCDAKY VWAATAGGVF QSITPIEIDM IVGKDREGFF TNGLALGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRVL VFVMGKEGVH GGGLNKKAYS MAKYLRDSGF
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P35080
Internal Search Terms :
PFN2, Profilin 2, PFL, Profilin 2 D3S1319E, PFN 2, PFN2, Profilin II, ProfilinII, Profilin2,ATGP0535-10ug,ATGP0535-20ug,ATGP0535-50ug,ATGP0535-100ug,ATGP0535-250ug,ATGP0535-500ug,ATGP0535-1mg,ATGP0535-10,ATGP0535-20,ATGP0535-50,ATGP0535-100,ATGP0535-250,ATGP0535-500,ATGP0535-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.