Recombinant human UBE2T protein | NKMAX ATGP0529 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human UBE2T protein

catalog :

ATGP0529

quantity :

20 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human UBE2T protein

Domain :

1-197aa

Catalog number (SKU) :

ATGP0529

NCBI :

NP_054895

Description :

uBE2T, also known as PIG50 or HSPC150, is a member of the E2 ubiquitin-conjugating enzyme family Involved in the protein degradation pathway. This protein catalyzes the ATP-dependent attachment of ubiquitin (ub) to target proteins, thereby tagging them for subsequent destruction by the proteasome. Additionally, uBE2T is thought to be a crucial component of the Faconi anemia pathway of DNA damage repair and, upon self-inactivation, may negatively regulate the Faconi pathway. Recombinant uBE2T protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Biquitin-conjugating enzyme E2 T, Cell proliferation-inducing gene 50 protein, E2 ubiquitin-conjugating enzyme T, Ubiquitin carrier protein T, Ubiquitin-protein ligase T, HSPC150, PIG50, FANCT

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Hao J., et al. (2008) Tumour Biol. 29(3):195-203. ;; Machida YJ., et al. (2006) Mol Cell. 23(4):589-96. ;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Ubiquitination

Molecular Weight :

23.6 kDa (205aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MQRASRLKRE LHMLATEPPP GITCWQDKDQ MDDLRAQILG GANTPYEKGV FKLEVIIPER YPFEPPQIRF LTPIYHPNID SAGRICLDVL KLPPKGAWRP SLNIATVLTS IQLLMSEPNP DDPLMADISS EFKYNKPAFL KNARQWTEKH ARQKQKADEE EMLDNLPEAG DSRVHNSTQK RKASQLVGIE KKFHPDVLEH HHHHH

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9NPD8

Internal Search Terms :

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more info or order :

NKMAX product webpage