protein

Recombinant human GOPC protein

ATGP0485

20 ug

70 USD

Recombinant human GOPC protein

278-454aa

ATGP0485

NP_001017408

GOPC, also known as PIST, is a PDZ domain-containing Golgi protein. This protein functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation. Additionally, GOPC is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy. Chromosomal aberrations in the gene encoding GOPC are found in glioblastoma multiform (GBM), a common and aggressive form of brain tumor, suggesting a role for mutated PIST in carcinogenesis. Recombinant GOPC protein was expressed in E. coli and purified by using conventional chromatography techniques.

Golgi-associated PDZ and coiled-coil motif-containing protein, CAL, dJ94G16.2, FIG, GOPC1, PIST, Golgi-associated PDZ and coiled-coil motif-containing protein CFTR associated ligand, dJ94G16.2, FIG Fused in glioblastoma, Golgi associated PDZ and coiled coil motif containing, Golgi associated PDZ and coiled coil motif containing protein, GOPC 1, OTTHuMP00000040403, PDZ protein interacting specifically with TC 10, PDZ protein interacting specifically with TC10, PDZ/coiled coil domain binding partner for the rho family GTPase TC 10, PDZ/coiled coil domain binding partner for the rho family GTPase TC10, Protein interacting specifically with Tc 10, Protein interacting specifically with Tc10.

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Cheng J., et al. (2002) J Biol Chem. 277(5):3520-9. ;; Yao R., et al. (2001) Biochem Biophys Res Commun. 286(4):771-8.;;

> 90% by SDS-PAGE

SDS-PAGE

Human

Adhesion & Movement

21.5 kDa (198aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

MGSSHHHHHH SSGLVPRGSH MIRKVLLLKE DHEGLGISIT GGKEHGVPIL ISEIHPGQPA DRCGGLHVGD AILAVNGVNL RDTKHKEAVT ILSQQRGEIE FEVVYVAPEV DSDDENVEYE DESGHRYRLY LDELEGGGNP GASCKDTSGE IKVLQGFNKK AVTDTHENGD LGTASETPLD DGASKLDDLH TLYHKKSY

His-Tag

E.coli

Recombinant Protein

Q9HD26

GOPC, Golgi-associated PDZ and coiled-coil motif-containing protein, CAL, dJ94G16.2, FIG, GOPC1, PIST, Golgi-associated PDZ and coiled-coil motif-containing protein CFTR associated ligand, dJ94G16.2, FIG Fused in glioblastoma, Golgi associated PDZ and coiled coil motif containing, Golgi associated PDZ and coiled coil motif containing protein, GOPC 1, OTTHuMP00000040403, PDZ protein interacting specifically with TC 10, PDZ protein interacting specifically with TC10, PDZ/coiled coil domain binding partner for the rho family GTPase TC 10, PDZ/coiled coil domain binding partner for the rho family GTPase TC10, Protein interacting specifically with Tc 10, Protein interacting specifically with Tc10.,ATGP0485-10ug,ATGP0485-20ug,ATGP0485-50ug,ATGP0485-100ug,ATGP0485-250ug,ATGP0485-500ug,ATGP0485-1mg,ATGP0485-10,ATGP0485-20,ATGP0485-50,ATGP0485-100,ATGP0485-250,ATGP0485-500,ATGP0485-1