product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human PDCD6IP protein
catalog :
ATGP0482
quantity :
20 ug
price :
70 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human PDCD6IP protein
Domain :
1-392aa
Catalog number (SKU) :
ATGP0482
NCBI :
NP_037506.2
Description :
Alix, also known as PDCD6IP, is a cytoplasmic protein that interacts with apoptosis-associated proteins (ALG-2 and PDCD6) and with the endocytosis-regulator CIN85. It's involved in concentration and sorting of cargo proteins of the multivesicular body for incorporation into intralumenal vesicles that are generated by invagination and scission from the limiting membrane of the endosome. Overexpression of this protein and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death. Recombinant PDCD6IP protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Programmed cell death 6 interacting protein, PDCD6-interacting protein, ALG-2 interacting protein X, ALG-2-interacting protein 1, Alix, AIP1, Hp95
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Morita E., et al. (2007) EMBO J. 26(19):4215-27. ;; Katoh K., et al. (2004) Arch Biochem Biophys. 421(1):159-65.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Apoptosis
Molecular Weight :
45.8 kDa (412aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MATFISVQLK KTSEVDLAKP LVKFIQQTYP SGGEEQAQYC RAAEELSKLR RAAVGRPLDK HEGALETLLR YYDQICSIEP KFPFSENQIC LTFTWKDAFD KGSLFGGSVK LALASLGYEK SCVLFNCAAL ASQIAAEQNL DNDEGLKIAA KHYQFASGAF LHIKETVLSA LSREPTVDIS PDTVGTLSLI MLAQAQEVFF LKATRDKMKD AIIAKLANQA ADYFGDAFKQ CQYKDTLPKE VFPVLAAKHC IMQANAEYHQ SILAKQQKKF GEEIARLQHA AELIKTVASR YDEYVNVKDF SDKINRALAA AKKDNDFIYH DRVPDLKDLD PIGKATLVKS TPVNVPISQK FTDLFEKMVP VSVQQSLAAY NQRKADLVNR SIAQMREATT LA
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q8WUM4
Internal Search Terms :
Alix,ATGP0482-10ug,ATGP0482-20ug,ATGP0482-50ug,ATGP0482-100ug,ATGP0482-250ug,ATGP0482-500ug,ATGP0482-1mg,ATGP0482-10,ATGP0482-20,ATGP0482-50,ATGP0482-100,ATGP0482-250,ATGP0482-500,ATGP0482-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.