product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human CDK2AP1 protein
catalog :
ATGP0480
quantity :
20 ug
price :
70 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human CDK2AP1 protein
Domain :
1-115aa
Catalog number (SKU) :
ATGP0480
NCBI :
NP_004633
Description :
CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Also, interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. Recombinant CDK2AP1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Cyclin-dependent kinase 2 associated protein 1, CDKAP1, DOC1, CDKA1, Cyclin-dependent kinase 2 associated protein 1 CDK2 A1, CDK2 associated protein 1, CDK2AP1, Cyclin dependent kinase 2 associated protein 1 Deleted in oral cancer 1, DOC 1, DOC 1 related protein, DOC 1R, DOC1R, Putative oral cancer suppressor.
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 2mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Tsuji T., et al. (1998) J Biol Chem. 273(12):6704-9.;; Hu MG., et al. (2004) Cancer Res. 64(2):490-9.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cell Cycle
Molecular Weight :
16.6 kDa (152aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSY KPNLAAHMPA AALNAAGSVH SPSTSMATSS QYRQLLSDYG PPSLGYTQGT GNSQVPQSKY AELLAIIEEL GKEIRPTYAG SKSAMERLKR GIIHARGLVR ECLAETERNA RS
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
O14519
Internal Search Terms :
CDK2AP1, Cyclin-dependent kinase 2 associated protein 1, CDKAP1, DOC1, CDKA1, Cyclin-dependent kinase 2 associated protein 1 CDK2 A1, CDK2 associated protein 1, CDK2AP1, Cyclin dependent kinase 2 associated protein 1 Deleted in oral cancer 1, DOC 1, DOC 1 related protein, DOC 1R, DOC1R, Putative oral cancer suppressor.,ATGP0480-10ug,ATGP0480-20ug,ATGP0480-50ug,ATGP0480-100ug,ATGP0480-250ug,ATGP0480-500ug,ATGP0480-1mg,ATGP0480-10,ATGP0480-20,ATGP0480-50,ATGP0480-100,ATGP0480-250,ATGP0480-500,ATGP0480-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.