Recombinant human PARP protein | NKMAX ATGP0469 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PARP protein

catalog :

ATGP0469

quantity :

20 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PARP protein

Domain :

662-1014aa

Catalog number (SKU) :

ATGP0469

NCBI :

AAH37545.1

Description :

PARP1 is a nuclear DNA-binding zinc finger protein which can exist as a homo- or hetero-dimer, and is strongly activated by DNA strand breaks. This protein involved in chromatin architecture and DNA metabolism, and participates in protein modification to enhance or repress transcription. PARP1 also plays a role in other cellular processes, including cell proliferation and differentiation. PARP-1 deficiencies lead to chromosomal instability due to higher frequencies of chromosome fusions and aneuploidy, suggesting that poly (ADPribosyl) ation contributes to the efficient maintenance of genome integrity. Recombinant PARP1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Poly (ADP-ribose) polymerase family member 1, ADPRT, ADPRT1, pADPRT, pADPRT-1, PARP, PARP-1, PPOL, Poly (ADP-ribose) polymerase family, member 1 ADP ribosyltransferase (NAD+, poly (ADP ribose) polymerase), ADPRT 1, msPARP, NAD(+) ADP ribosyltransferase 1, pADPRT 1, PARP 1, PARP1, Poly (ADP ribose) polymerase 1, poly(ADP ribose) synthetase, poly(ADP ribosyl)transferase, Poly[ADP ribose] synthetase 1, sPARP 1, sPARP1.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Dantzer F., et al. (1998) Nucleic Acids Res. 26(8):1891-8. ;; Li Y., et al. (2006) Mol Cell Endocrinol. 257-258:35-46.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

39.6 kDa (354aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MKSKLPKPVQ DLIKMIFDVE SMKKAMVEYE IDLQKMPLGK LSKRQIQAAY SILSEVQQAV SQGSSDSQIL DLSNRFYTLI PHDFGMKKPP LLNNADSVQA KAEMLDNLLD IEVAYSLLRG GSDDSSKDPI DVNYEKLKTD IKVVDRDSEE AEIIRKYVKN THATTHNAYD LEVIDIFKIE REGECQRYKP FKQLHNRRLL WHGSRTTNFA GILSQGLRIA PPEAPVTGYM FGKGIYFADM VSKSANYCHT SQGDPIGLIL LGEVALGNMY ELKHASHISK LPKGKHSVKG LGKTTPDPSA NISLDGVDVP LGTGISSGVN DTSLLYNEYI VYDIAQVNLK YLLKLKFNFK TSLW

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P09874

Internal Search Terms :

PARP, Poly (ADP-ribose) polymerase family member 1, ADPRT, ADPRT1, pADPRT, pADPRT-1, PARP, PARP-1, PPOL, Poly (ADP-ribose) polymerase family, member 1 ADP ribosyltransferase (NAD+, poly (ADP ribose) polymerase), ADPRT 1, msPARP, NAD(+) ADP ribosyltransferase 1, pADPRT 1, PARP 1, PARP1, Poly (ADP ribose) polymerase 1, poly(ADP ribose) synthetase, poly(ADP ribosyl)transferase, Poly[ADP ribose] synthetase 1, sPARP 1, sPARP1.,ATGP0469-10ug,ATGP0469-20ug,ATGP0469-50ug,ATGP0469-100ug,ATGP0469-250ug,ATGP0469-500ug,ATGP0469-1mg,ATGP0469-10,ATGP0469-20,ATGP0469-50,ATGP0469-100,ATGP0469-250,ATGP0469-500,ATGP0469-1

more info or order :

NKMAX product webpage