Recombinant human ENSA protein | NKMAX ATGP0457 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human ENSA protein

catalog :

ATGP0457

quantity :

20 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human ENSA protein

Domain :

1-121aa

Catalog number (SKU) :

ATGP0457

NCBI :

NP_004427

Description :

ENSA, also known as alpha endosulfine, belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein is expressed in a wide range of tissues including muscle, brain, and endocrine tissues. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SuR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. Recombinant ENSA protein was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Alpha endosulfine isoform 3, ARPP-19e, Alpha endosulfine isoform 3 Alpha endosulfine, ARPP 19e, Endosulfine alpha.

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.2mM PMSF

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Heron L., et al. (1998) Proc Natl Acad Sci u S A. 95(14):8387-91. ;; Kim SH., et al. (2001) J Neural Transm Suppl. 61:1-9. ;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

15.5 kDa (141aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O43768

Internal Search Terms :

ENSA, Alpha endosulfine isoform 3, ARPP-19e, Alpha endosulfine isoform 3 Alpha endosulfine, ARPP 19e, Endosulfine alpha.,ATGP0457-10ug,ATGP0457-20ug,ATGP0457-50ug,ATGP0457-100ug,ATGP0457-250ug,ATGP0457-500ug,ATGP0457-1mg,ATGP0457-10,ATGP0457-20,ATGP0457-50,ATGP0457-100,ATGP0457-250,ATGP0457-500,ATGP0457-1

more info or order :

NKMAX product webpage