Recombinant human SDNSF/MCFD2 protein | NKMAX ATGP0455 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human SDNSF/MCFD2 protein

catalog :

ATGP0455

quantity :

20 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human SDNSF/MCFD2 protein

Domain :

27-146aa

Catalog number (SKU) :

ATGP0455

NCBI :

NP_644808

Description :

Multiple coagulation factor deficiency 2 (MCFD2), also known as SDNSF. This is expressed by neural stem/progenitor cells of the hippocampus, and localized to region where neurogenesis persists throughout life. It has been found to prevent NSC cell death and to maintain stem cell characteristics. This protein forms a complex with LAMN1 that facilitates the transport of coagulation factors V and VIII from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment. Mutations in the MCFD2 gene may cause Factor V and Factor VIII combined deficiency. Recombinant human MCFD2, fused to T7-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Multiple coagulation factor deficiency 2, SDNSF, LMAN1IP, Multiple coagulation factor deficiency 2 MCFD 2, DKFZp686G21263, F5F8D, Neural stem cell derived neuronal survival protein, Multiple coagulation factor deficiency protein 2.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 100mM NaCl, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Zhanq B., et al. (2005) Biol Chem. 280(27):25881-6. ;; Mohanty D., et al. (2005) Am J Hematol. 79:262-266. ;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

15.1 kDa (136aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MASMTGGQQM GRGSHMEEPA ASFSQPGSMG LDKNTVHDQE HIMEHLEGVI NKPEAEMSPQ ELQLHYFKMH DYDGNNLLDG LELSTAITHV HKEEGSEQAP LMSEDELINI IDGVLRDDDK NNDGYIDYAE FAKSLQ

Tag :

T7-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q8NI22

Internal Search Terms :

SDNSF, MCFD2, Multiple coagulation factor deficiency 2, SDNSF, LMAN1IP, Multiple coagulation factor deficiency 2 MCFD 2, DKFZp686G21263, F5F8D, Neural stem cell derived neuronal survival protein, Multiple coagulation factor deficiency protein 2.,ATGP0455-10ug,ATGP0455-20ug,ATGP0455-50ug,ATGP0455-100ug,ATGP0455-250ug,ATGP0455-500ug,ATGP0455-1mg,ATGP0455-10,ATGP0455-20,ATGP0455-50,ATGP0455-100,ATGP0455-250,ATGP0455-500,ATGP0455-1

more info or order :

NKMAX product webpage