Recombinant human LIN-28A protein | NKMAX ATGP0412 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human LIN-28A protein

catalog :

ATGP0412

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human LIN-28A protein

Domain :

42-209aa

Catalog number (SKU) :

ATGP0412

NCBI :

NP_078950

Description :

Lin-28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. It is marker of undifferentiated human embryonic stem cells and has been used to enhance the efficiency of the formation of induced pluripotent stem (iPS) cells from human fibroblasts. It has also been shown to bind to the let-7 pre-miRNA and block production of the mature let-7 microRNA in mouse embryonic stem cells. Recombinant Lin28 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Zinc finger CCHC domain-containing protein 1, ZCCHC1, Tex17, RNA binding protein lin 28, LIN28A, LIN-28, Lin 28 homolog A, Lin 28 homolog, FLJ12457, CSDD1,

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl, 0.1mM PMSF

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Moss E.G., et al. (2003) Dev. Biol. 258:432-442;; Heo I., et al. (2009) Cell. 138:696-708.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

21.1 kDa (191aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH RSMGICKWFN VRMGFGFLSM TARAGVALDP PVDVFVHQSK LHMEGFRSLK EGEAVEFTFK KSAKGLESIR VTGPGGVFCI GSERRPKGKS MQKRRSKGDR CYNCGGLDHH AKECKLPPQP KKCHFCQSIS HMVASCPLKA QQGPSAQGKP TYFREEEEEI HSPTLLPEAQ N

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9H9Z2

Internal Search Terms :

Zinc finger CCHC domain-containing protein 1 AL024421.Lin 28, Zinc finger CCHC domain-containing protein 1, Zinc finger CCHC domain containing protein 1, ZCCHC1, Tex17, RNA binding protein lin 28, LIN28A, LIN-28A, LIN-28, LIN28, LIN 28, LIN 28A, LIN 28 A, Lin 28 homolog A, Lin 28 homolog, FLJ12457, CSDD1, "Lin 28 homolog (C, elegans)", ATGP0412-10ug, ATGP0412-20ug, ATGP0412-50ug, ATGP0412-100ug, ATGP0412-250ug, ATGP0412-500ug, ATGP0412-1mg, ATGP0412-010, ATGP0412-020, ATGP0412-050, ATGP0412-100, ATGP0412-250, ATGP0412-500, ATGP0412-01M

more info or order :

NKMAX product webpage