protein

Recombinant human Annexin A5/ANXA5 protein

ATGP0406

20 ug

70 USD

Recombinant human Annexin A5/ANXA5 protein

1-320aa

ATGP0406

NP_001145.1

Annexin A5, also known as Annexin V, belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin A5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Recombinant Annexin A5 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Vascular anticoagulant-alpha, VAC-alpha, Thromboplastin inhibitor, PP4, Placental anticoagulant protein I, PAP I, Lipocortin V, ENX2, Endonexin II, CPB-I, Calphobindin I, ANX5, ANX A5, Annexin V, Annexin A5, Annexin 5, Anchorin CII

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Frey B., et al. (2009) J Immunotoxicol. 6(4):209-16. ;; Steele AJ., et al. (2009) Blood. 114(6):1217-25.;;

> 95% by SDS-PAGE

SDS-PAGE

Human

Apoptosis

35.9 kDa (320aa) confirmed by MALDI-TOF

MAQVLRGTVT DFPGFDERAD AETLRKAMKG LGTDEESILT LLTSRSNAQR QEISAAFKTL FGRDLLDDLK SELTGKFEKL IVALMKPSRL YDAYELKHAL KGAGTNEKVL TEIIASRTPE ELRAIKQVYE EEYGSSLEDD VVGDTSGYYQ RMLVVLLQAN RDPDAGIDEA QVEQDAQALF QAGELKWGTD EEKFITIFGT RSVSHLRKVF DKYMTISGFQ IEETIDRETS GNLEQLLLAV VKSIRSIPAY LAETLYYAMK GAGTDDHTLI RVMVSRSEID LFNIRKEFRK NFATSLYSMI KGDTSGDYKK ALLLLCGEDD

Non-Tagged

E.coli

Recombinant Protein

P08758

Annexin V, Annexin V, ANX5, ENX2, PP4, Anchorin CII, Annexin 5, Annexin A5, ANX A5, Calphobindin I, Endonexin II, Lipocortin V, PAP I, Placental anticoagulant protein I.,ATGP0406-10ug,ATGP0406-20ug,ATGP0406-50ug,ATGP0406-100ug,ATGP0406-250ug,ATGP0406-500ug,ATGP0406-1mg,ATGP0406-10,ATGP0406-20,ATGP0406-50,ATGP0406-100,ATGP0406-250,ATGP0406-500,ATGP0406-1

Shen MY, et al. [Gly14]-Humanin Ameliorates High Glucose-Induced Apoptosis by Inhibiting the Expression of MicroRNA-155 in Endothelial Microparticles. (Diabetes Metab Syndr Obes. 2021){https://pubmed.ncbi.nlm.nih.gov/34079312/}