Recombinant human NQO1 protein | NKMAX ATGP0392 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human NQO1 protein

catalog :

ATGP0392

quantity :

10 ug

price :

120 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human NQO1 protein

Domain :

1-274aa

Catalog number (SKU) :

ATGP0392

NCBI :

NP_000894.1

Description :

NQO1 is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This protein apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 functions as an important part of cellular antioxidant defense by detoxifying quinines thus preventing the formation of reactive oxygen species. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer's disease (AD). Recombinant NQO1 protein was expressed in E. coli and purified by using conventional chromatography techniques

Alternative Names :

NAD(P)H quinone dehydrogenase 1, NMOR1, DIA4, Diaphorase, NADH/NADPH, Cytochrome b-5 reductase, NAD(P)H dehydrogenase, Quinone 1, DHQU, QR1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Jaiswal AK., et al. (1988) J Biol Chem. 263(27):13572-8. ;; Traver RD., et al. (1992) Cancer Res. 52(4):797-802.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Redox Proteins

Molecular Weight :

33.0 kDa (294aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MVGRRALIVL AHSERTSFNY AMKEAAAAAL KKKGWEVVES DLYAMNFNPI ISRKDITGKL KDPANFQYPA ESVLAYKEGH LSPDIVAEQK KLEAADLVIF QFPLQWFGVP AILKGWFERV FIGEFAYTYA AMYDKGPFRS KKAVLSITTG GSGSMYSLQG IHGDMNVILW PIQSGILHFC GFQVLEPQLT YSIGHTPADA RIQILEGWKK RLENIWDETP LYFAPSSLFD LNFQAGFLMK KEVQDEEKNK KFGLSVGHHL GKSIPTDNQI KARK

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P15559

Internal Search Terms :

NQO1,ATGP0392-10ug,ATGP0392-20ug,ATGP0392-50ug,ATGP0392-100ug,ATGP0392-250ug,ATGP0392-500ug,ATGP0392-1mg,ATGP0392-10,ATGP0392-20,ATGP0392-50,ATGP0392-100,ATGP0392-250,ATGP0392-500,ATGP0392-1

more info or order :

NKMAX product webpage