Recombinant human TCL1A protein | NKMAX ATGP0391 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TCL1A protein

catalog :

ATGP0391

quantity :

20 ug

price :

55 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TCL1A protein

Domain :

1-114aa

Catalog number (SKU) :

ATGP0391

NCBI :

NP_001092195.1

Description :

TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E. coli and purified by using conventional chromatography techniques

Alternative Names :

T-cell leukemia/lymphoma 1A, TCL1, TCL-1, protein p14TCL1, Oncogene TCL1, T-cell leukemia/lymphoma 1A anti TCL1A, P14 TCL1, P14 TCL1 protein, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, TCL 1 protein, TCL1 oncogene, TCL1 PEN, TCL1A, TCL1A.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Herling M., et al. (2006) Leukemia. 20(2):280-5.;; Hoyer KK., et al. (2005) J Immunol. 175(2):864-73.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

13.4 kDa (114aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Amino Acid Sequence :

MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P56279

Internal Search Terms :

TCL1A, T-cell leukemia/lymphoma 1A, TCL1, TCL-1, protein p14TCL1, Oncogene TCL1, T-cell leukemia/lymphoma 1A anti TCL1A, P14 TCL1, P14 TCL1 protein, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, TCL 1 protein, TCL1 oncogene, TCL1 PEN, TCL1A, TCL1A.,ATGP0391-10ug,ATGP0391-20ug,ATGP0391-50ug,ATGP0391-100ug,ATGP0391-250ug,ATGP0391-500ug,ATGP0391-1mg,ATGP0391-10,ATGP0391-20,ATGP0391-50,ATGP0391-100,ATGP0391-250,ATGP0391-500,ATGP0391-1

more info or order :

NKMAX product webpage