protein

Recombinant human CCL28/MEC protein

ATGP0387

20 ug

105 USD

Recombinant human CCL28/MEC protein

23-127aa

ATGP0387

NP_683513

CCL28, also known as chemokine (C-C motif) ligand 28 or mucosae-associated epithelial chemokine (MEC), belongs to the subfamily of small cytokine CC proteins. CCL28 is expressed by columnar epithelial cells in the gut, lung, breast and the salivary glands and drives the mucosal homing of T and B lymphocytes that express CCR10, and the migration of eosinophils expressing CCR3. This chemokine is constitutively expressed in the colon, but its levels can be increased by pro-inflammatory cytokines and certain bacterial products implying a role in effector cell recruitment to sites of epithelial injury. Recombinant CCL28 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

C-C motif chemokine ligand 28, Mucosae-associated epithelial chemokine, MEC, Protein CCK1, Small-inducible cytokine A28, SCYA28, CCK1

1mg/ml (determined by Bradford assay)

Liquid in. 10mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Pacheco-Rodriguez G., et al. (2009) J Immunol. 182(3):1270-7. ;; Sundstrom P., et al. (2008) Eur J Immunol. 38(12):3327-38.;;

> 90% by SDS-PAGE

SDS-PAGE

Human

Hormones & Cytokines

14.3 kDa (126aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

MGSSHHHHHH SSGLVPRGSH MILPIASSCC TEVSHHISRR LLERVNMCRI QRADGDCDLA AVILHVKRRR ICVSPHNHTV KQWMKVQAAK KNGKGNVCHR KKHHGKRNSN RAHQGKHETY GHKTPY

His-Tag

E.coli

Recombinant Protein

Q9NRJ3

CCL28, Chemokine (C-C motif) ligand 28, CCK1, MEC, SCYA28, Chemokine (C-C motif) ligand 28, CCL28, CC chemokine CCL28, mucosae-associated epithelial chemokine, small inducible cytokine subfamily A (Cys-Cys) member 28, small inducible cytokine A28,ATGP0387-10ug,ATGP0387-20ug,ATGP0387-50ug,ATGP0387-100ug,ATGP0387-250ug,ATGP0387-500ug,ATGP0387-1mg,ATGP0387-10,ATGP0387-20,ATGP0387-50,ATGP0387-100,ATGP0387-250,ATGP0387-500,ATGP0387-1