Recombinant human NDRG1 protein | NKMAX ATGP0386 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human NDRG1 protein

catalog :

ATGP0386

quantity :

20 ug

price :

55 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human NDRG1 protein

Domain :

1-394aa

Catalog number (SKU) :

ATGP0386

NCBI :

NP_006087

Description :

N-myc downstream regulated gene (NDRG) -1 is one of 4 members of the NDRG alpha/beta-hydrolase family. This protein is classified in databases as a tumor suppressor and heavy metal-response protein. Its functions include cell-cycle regulation, cellular differentiation, apoptosis, hypoxia response and metal-ion sensing. Mutation in the NDRG1 gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom (HMSNL), a severe autosomal recessive form of Charcot-Marie-Tooth (CMT) disease. Recombinant human NDRG1, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

N-myc downstream regulated 1, CAP43, CMT4D, DRG1, GC4, HMSNL, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5, N-myc downstream regulated 1 TDD5, 42 kDa, anti-GC4, cmt4d, Differentiation related gene1 protein, Drg 1, hmsnl, Human mRNA for RTP complete cds, NDRG1, tdds, N myc downstream regulated gene 1, N myc downstream regulated gene 1 protein, Ndr 1, ndr1, NDRG 1, NDRG1 protein, Protein nickel specific induction protein, Nickel specific induction protein Cap43, nmsl, Nmyc downstream regulated, reduced in tumor, reducin, Nmyc downstream regulated gene1, Nmyc downstream regulated gene1 protein, Protein regulated by oxygen 1, Protein regulated by oxygen1, proxy1, Reducing agents and tunicamycin responsive protein, tunicamycin-responsive protein

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1mM PMSF, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Richardson DR., et al. (2008) Biochim Biophys Acta. 1783(10):1981-92.;; Costa M., et al. (2008) Carcinogenesis. 29(1):2-8.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

43.9 kDa (402aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MSREMQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSVHVTLCG TPKGNRPVIL TYHDIGMNHK TCYNPLFNYE DMQEITQHFA VCHVDAPGQQ DGAASFPAGY MYPSMDQLAE MLPGVLQQFG LKSIIGMGTG AGAYILTRFA LNNPEMVEGL VLINVNPCAE GWMDWAASKI SGWTQALPDM VVSHLFGKEE MQSNVEVVHT YRQHIVNDMN PGNLHLFINA YNSRRDLEIE RPMPGTHTVT LQCPALLVVG DSSPAVDAVV ECNSKLDPTK TTLLKMADCG GLPQISQPAK LAEAFKYFVQ GMGYMPSASM TRLMRSRTAS GSSVTSLDGT RSRSHTSEGT RSRSHTSEGT RSRSHTSEGA HLDITPNSGA AGNSAGPKSM EVSC

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q92597

Internal Search Terms :

NDRG1,ATGP0386-10ug,ATGP0386-20ug,ATGP0386-50ug,ATGP0386-100ug,ATGP0386-250ug,ATGP0386-500ug,ATGP0386-1mg,ATGP0386-10,ATGP0386-20,ATGP0386-50,ATGP0386-100,ATGP0386-250,ATGP0386-500,ATGP0386-1

more info or order :

NKMAX product webpage