Recombinant human GPI protein | NKMAX ATGP0348 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human GPI protein

catalog :

ATGP0348

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human GPI protein

Domain :

1-558aa

Catalog number (SKU) :

ATGP0348

NCBI :

NP_000166

Description :

Glucose-6-phosphate isomerase, also known as GPI, belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. Mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Recombinant human GPI, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Glucose-6-phosphate isomerase, GPI, AMF, GNPI, NLK, PGI, PHI, SA36, EC 5.3.1.9, Neuroleukin, Phosphoglucose isomerase, Phosphohexose isomerase, SA 36, Sperm antigen 36, G6PI, Glucose-6-phosphate isomerase

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Lin HY., et al. (2009) Biochim Biophys Acta. 1794(2):315-23. ;; Beutler E., et al. (1997) Blood cells Mol. 23:402-409. ;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Enzymes & Proteases

Molecular Weight :

65.3 kDa (578aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MAALTRDPQF QKLQQWYREH RSELNLRRLF DANKDRFNHF SLTLNTNHGH ILVDYSKNLV TEDVMRMLVD LAKSRGVEAA RERMFNGEKI NYTEGRAVLH VALRNRSNTP ILVDGKDVMP EVNKVLDKMK SFCQRVRSGD WKGYTGKTIT DVINIGIGGS DLGPLMVTEA LKPYSSGGPR VWYVSNIDGT HIAKTLAQLN PESSLFIIAS KTFTTQETIT NAETAKEWFL QAAKDPSAVA KHFVALSTNT TKVKEFGIDP QNMFEFWDWV GGRYSLWSAI GLSIALHVGF DNFEQLLSGA HWMDQHFRTT PLEKNAPVLL ALLGIWYINC FGCETHAMLP YDQYLHRFAA YFQQGDMESN GKYITKSGTR VDHQTGPIVW GEPGTNGQHA FYQLIHQGTK MIPCDFLIPV QTQHPIRKGL HHKILLANFL AQTEALMRGK STEEARKELQ AAGKSPEDLE RLLPHKVFEG NRPTNSIVFT KLTPFMLGAL VAMYEHKIFV QGIIWDINSF DQWGVELGKQ LAKKIEPELD GSAQVTSHDA STNGLINFIK QQREARVQ

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P06744

Internal Search Terms :

GPI, Glucose-6-phosphate isomerase, GPI, AMF, GNPI, NLK, PGI, PHI, SA36, EC 5.3.1.9, Neuroleukin, Phosphoglucose isomerase, Phosphohexose isomerase, SA 36, Sperm antigen 36, G6PI, Glucose-6-phosphate isomerase,ATGP0348-10ug,ATGP0348-20ug,ATGP0348-50ug,ATGP0348-100ug,ATGP0348-250ug,ATGP0348-500ug,ATGP0348-1mg,ATGP0348-10,ATGP0348-20,ATGP0348-50,ATGP0348-100,ATGP0348-250,ATGP0348-500,ATGP0348-1

References with this Product :

Tanie Y, et al. Extracellular Neuroleukin Enhances Neuroleukin Secretion From Astrocytes and Promotes Axonal Growth in vitro and in vivo. (Front Pharmacol. 2018){https://pubmed.ncbi.nlm.nih.gov/30459611/};;Tanie Y, et al. GRP78-Mediated Signaling Contributes to Axonal Growth Resulting in Motor Function Recovery in Spinal Cord-Injured Mice. (Front Pharmacol. 2020){https://pubmed.ncbi.nlm.nih.gov/32547396/}

more info or order :

NKMAX product webpage