protein

Recombinant human Glutathione S-transferase theta 1/GSTT1 protein

ATGP0346

20 ug

80 USD

Recombinant human Glutathione S-transferase theta 1/GSTT1 protein

1-240aa

ATGP0346

AAH07065.1

Glutathione S-transferase theta 1 (GSTT1) is one of the GSTs' four main classes: alpha, mu, pi, theta. This enzyme is involved in activation and detoxification reactions and catalyzes the conjugation of industrial chemicals, e. g. epoxybutane, ethylene oxides, halomethane with glutathione. The absence of the GSTTI enzyme, might determine the individual risk for development of acquired aplastic anemia and acute myeloid leukemia. Recombinant human GSTT1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Glutathione S-transferase theta 1, GSTT1, GST class-theta-1, Glutathione transferase T1-1, Glutathione S-transferase theta 1 EC 2.5.1.18, Glutathione S transferase 5, Glutathione S transferase theta 1, GST class theta 1, Glutathione transferase T1 1, GST 5 5, GST CL1

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Faramawy MM., et al. (2009). J Crit Care. 24(3):e7-10.;; Delpisheh A., et al. (2009). Eur J Obstet Gynecol Reprod Biol. 143(1):38-42.;;

> 90% by SDS-PAGE

SDS-PAGE

Human

Enzymes & Proteases

31.5 kDa (277aa) confirmed by MALDI-TOF

MGL ELYLDLLSQP CRAVYIFAKK NDIPFELRIV DLIKGQHLSD ACAQVNPLKK VPALKDGDFT LTESVAILLY LTRKYKVPDY WYPQDLQARA RVDEYLAWQH TTLRRSCLRA LWHKVMFPVF LGEPVSPQTL AATLAELDVT LQLLEDKFLQ NKAFLTGPHI SLADLVAITE LMHPVGAGCQ VFEGRPKLAT WRQRVEAAVG EDLFQEAHEV ILKAKDFPPA DPTIKQKLMP WVLAMIR

His-Tag

E.coli

Recombinant Protein

P30711

Glutathione S-transferase theta1, GSTT1, Glutathione S-transferase theta 1, Glutathione S-transferase theta 1, GSTT1, GST class-theta-1, Glutathione transferase T1-1, Glutathione S-transferase theta 1 EC 2.5.1.18, Glutathione S transferase 5, Glutathione S transferase theta 1, GST class theta 1, Glutathione transferase T1 1, GST 5 5, GST CL1,ATGP0346-10ug,ATGP0346-20ug,ATGP0346-50ug,ATGP0346-100ug,ATGP0346-250ug,ATGP0346-500ug,ATGP0346-1mg,ATGP0346-10,ATGP0346-20,ATGP0346-50,ATGP0346-100,ATGP0346-250,ATGP0346-500,ATGP0346-1

Toyoda Y, et al. Spontaneous Production of Glutathione-Conjugated Forms of 1,2-Dichloropropane: Comparative Study on Metabolic Activation Processes of Dihaloalkanes Associated with Occupational Cholangiocarcinoma. (Oxid Med Cell Longev. 2017){https://pubmed.ncbi.nlm.nih.gov/28555163/}