Recombinant human PEDF/SERPINF1 protein | NKMAX ATGP0342 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PEDF/SERPINF1 protein

catalog :

ATGP0342

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PEDF/SERPINF1 protein

Domain :

20-418aa

Catalog number (SKU) :

ATGP0342

NCBI :

NP_002606.3

Description :

PEDF, also known as SERPINF1, is an extracellular neurotrophic agent, first identified as a secreted product in conditioned medium from cultured fetal human retinal pigment epithelial (RPE) cells. It was reported that PEDF isolated from medium conditioned by human fetal RPE primary cultures promotes neurite outgrowth in cultured human retinoblastoma Y-79 cells. PEDF is also a member of the serpin family, a group of serine protease inhibitors. As PEDF does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. Recombinant PEDF protein containing a natural variant T72M was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Pigment epithelium-derived factor, Pigment epithelium-derived factor, EPC-1, PIG35, SERPINF1, Pigment epithelium-derived factor EPC 1, EPC1, PIG 35, Pigment epithelium derived factor, Proliferation inducing protein 35, SERPIN F1, Serpin peptidase inhibitor clade F member 1, SERPINF 1,

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Steele FR., et al. (1993) Proc Natl Acad Sci u S A. 90(4):1526-30. ;; Becerra SP., et al. (1995) J Biol Chem. 270(43):25992-9.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Angiogenesis

Molecular Weight :

46.7 kDa (420aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MQNPASPPEE GSPDPDSTGA LVEEEDPFFK VPVNKLAAAV SNFGYDLYRV RSSMSPTTNV LLSPLSVATA LSALSLGAEQ RTESIIHRAL YYDLISSPDI HGTYKELLDT VTAPQKNLKS ASRIVFEKKL RIKSSFVAPL EKSYGTRPRV LTGNPRLDLQ EINNWVQAQM KGKLARSTKE IPDEISILLL GVAHFKGQWV TKFDSRKTSL EDFYLDEERT VRVPMMSDPK AVLRYGLDSD LSCKIAQLPL TGSMSIIFFL PLKVTQNLTL IEESLTSEFI HDIDRELKTV QAVLTVPKLK LSYEGEVTKS LQEMKLQSLF DSPDFSKITG KPIKLTQVEH RAGFEWNEDG AGTTPSPGLQ PAHLTFPLDY HLNQPFIFVL RDTDTGALLF IGKILDPRGP

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P36955

Internal Search Terms :

SERPIN F1, PEDF, Pigment epithelium-derived factor, Pigment epithelium-derived factor, EPC-1, PIG35, SERPINF1, Pigment epithelium-derived factor EPC 1, EPC1, PIG 35, Pigment epithelium derived factor, Proliferation inducing protein 35, SERPIN F1, Serpin peptidase inhibitor clade F member 1, SERPINF 1,ATGP0342-10ug,ATGP0342-20ug,ATGP0342-50ug,ATGP0342-100ug,ATGP0342-250ug,ATGP0342-500ug,ATGP0342-1mg,ATGP0342-10,ATGP0342-20,ATGP0342-50,ATGP0342-100,ATGP0342-250,ATGP0342-500,ATGP0342-1

more info or order :

NKMAX product webpage