Recombinant human SAP18 protein | NKMAX ATGP0340 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human SAP18 protein

catalog :

ATGP0340

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human SAP18 protein

Domain :

20-172aa

Catalog number (SKU) :

ATGP0340

NCBI :

NP_005861.2

Description :

SAP18, also known as Sin3A-associated protein, is component of the histone deacetylase complex that plays an important role in the regulation of eukaryotic gene expression. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. It also has been shown to play a key role in gene-specific recruitment of the HDAC complex by a number of transcription factors including Gli, GAGA, and Bicoid. Recombinant SAP18 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Sin3A-associated protein 18kDa, Sin3A-associated protein, 2HOR0202, SAP18P, SAP18, Sin3A-associated protein, 18kDa Histone deacetylase complex subunit SAP18, Sin3-associated polypeptide p18.

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 30% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Zhang Y., et al. (1997) Cell. 89(3):357-64. ;; Matyash A, et al. (2009) J Biol Chem. 284(5):3012-20.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

19.7 kDa (173aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MAVESRVTQE EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT WMDATLKELT SLVKEVYPEA RKKGTHFNFA IVFTDVKRPG YRVKEIGSTM SGRKGTDDSM TLQSQKFQIG DYLDIAITPP NRAPPPSGRM RPY

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O00422

Internal Search Terms :

SAP18, Sin3A-associated protein 18kDa, Sin3A-associated protein, 2HOR0202, SAP18P, SAP18, Sin3A-associated protein, 18kDa Histone deacetylase complex subunit SAP18, Sin3-associated polypeptide p18.,ATGP0340-10ug,ATGP0340-20ug,ATGP0340-50ug,ATGP0340-100ug,ATGP0340-250ug,ATGP0340-500ug,ATGP0340-1mg,ATGP0340-10,ATGP0340-20,ATGP0340-50,ATGP0340-100,ATGP0340-250,ATGP0340-500,ATGP0340-1

more info or order :

NKMAX product webpage