Recombinant human BMP-14/GDF-5 protein | NKMAX ATGP0334 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human BMP-14/GDF-5 protein

catalog :

ATGP0334

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human BMP-14/GDF-5 protein

Domain :

382-501aa

Catalog number (SKU) :

ATGP0334

NCBI :

NP_000548

Description :

Growth differentiation factor 5 (GDF-5) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This protein plays a role in chondrogenesis and chondrocyte metabolism, tendon and ligament tissue formation, and bone repair. It also increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinson's disease. GDF-5, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Alternative Names :

Growth differentiation factor 5, Bone morphogenetic protein 14 (BMP-14), Cartilage-derived morphogenetic protein 1 (CDMP-1), Lipopolysaccharide-associated protein 4 (LAP-4; LPS-associated protein 4), Radotermin, BMP14, CDMP1, LAP4, OS5, SYNS2

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 10mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Feng G., et al. (2008). Growth Factor. 26(3):132-42;; Sullivan AM., et al. (2005). J Anat. 207(3):219-26.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

15.8 kDa (141aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MAPLATRQGK RPSKNLKARC SRKALHVNFK DMGWDDWIIA PLEYEAFHCE GLCEFPLRSH LEPTNHAVIQ TLMNSMDPES TPPTCCVPTR LSPISILFID SANNVVYKQY EDMVVESCGC R

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P43026

Internal Search Terms :

BMP 14, BMP14, BMP-14, Bone morphogenetic protein 14, Cartilage derived morphogenetic protein 1, Cartilage-derived morphogenetic protein 1, CDMP 1, CDMP1, CDMP-1, GDF 5, GDF5, GDF-5, Growth differentiation factor 5, LAP 4, LAP4, LAP-4, Lipopolysaccharide associated protein 4, Lipopolysaccharide-associated protein 4, LPS associated protein 4, LPS-associated protein 4, OS5, Radotermin, SYNS2, ATGP0334-10ug, ATGP0334-20ug, ATGP0334-50ug, ATGP0334-100ug, ATGP0334-250ug, ATGP0334-500ug, ATGP0334-1mg, ATGP0334-010, ATGP0334-020, ATGP0334-050, ATGP0334-100, ATGP0334-250, ATGP0334-500, ATGP0334-01M

more info or order :

NKMAX product webpage