Recombinant human Troponin C2/TNNC2 protein | NKMAX ATGP0332 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Troponin C2/TNNC2 protein

catalog :

ATGP0332

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Troponin C2/TNNC2 protein

Domain :

1-160aa

Catalog number (SKU) :

ATGP0332

NCBI :

NP_003270.1

Description :

Troponin C, skeletal muscle, also known as TNNC2, is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I (Tn-1), Troponin T (Tn-T) and Troponin C (Tn-C). Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. Mutations in all components of this complex have been associated with skeletal muscle disease. Recombinant human Troponin C was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

Troponin C2, Troponin C1 slow, Troponin C type 2 (fast), Troponin C type 1 (slow), Troponin C skeletal muscle, Troponin C, TNNC2, TNNC, Slow skeletal and cardiac muscles, Skeletal troponin C, Skeletal muscle TNNC1, Fast skeletal type, Fast skeletal muscle troponin C, FAP85, CFAP85, Cardiac troponin C

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 100mM NaCl, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Prentice H., et al. (1994). J Mol Cell Cardial. 26(10):1393-401. ;; Gahlmann R., et al. (1988). J Mol Biol. 201(2):379-91. ;; Li Y., et al. (2008). Hereditas. 145(6):274-82.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cytoskeleton

Molecular Weight :

18.1 kDa (160aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P02585

Internal Search Terms :

Troponin C (1160aa), Troponin C skeletal muscle, Troponin C, skeletal muscle, TNNC2, Troponin C, skeletal muscle TNNC1, Cardiac troponin C, TNNC, Troponin C1 slow, Fast skeletal muscle troponin C, Skeletal troponin C, Troponin C type 1 (slow), Troponin C type 2 (fast), Troponin C, slow skeletal and cardiac muscles,ATGP0332-10ug,ATGP0332-20ug,ATGP0332-50ug,ATGP0332-100ug,ATGP0332-250ug,ATGP0332-500ug,ATGP0332-1mg,ATGP0332-10,ATGP0332-20,ATGP0332-50,ATGP0332-100,ATGP0332-250,ATGP0332-500,ATGP0332-1

more info or order :

NKMAX product webpage