protein

Recombinant human Troponin T protein

ATGP0329

20 ug

105 USD

Recombinant human Troponin T protein

1-285aa

ATGP0329

NP_001001431.1

Troponin T, also known as TNNT2, is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with restrictive and dilated cardiomyopathy. Recombinant human TNNT2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Troponin T type 2 cardiac isoform 3, Troponin T type 2, cardiac isoform 3, CMH2, CMPD2, cTnT, RCM3, TnTC, Troponin T type 2, cardiac isoform 3 Cardiac muscle troponin T, MGC3889, TNNT 2, TNNT2, Cardiomyopathy hypertrophic 2, Cardiomyopathy dilated 1D (autosomal dominant), CMD1D, Troponin T cardiac muscle, Troponin T type 2 (cardiac), Troponin T type 2 cardiac, Troponin T2 cardiac.

0.25mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.5M NaCl, 0.1mM PMSF, 1mM DTT, 100mM imidazole

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Yu H., et al. (2009), Proteomics. 9(3):504-11.;; Morita H., et al. (2008). N Engl J Med. 358(18):1899-908.;;

> 90% by SDS-PAGE

SDS-PAGE

Human

Cytoskeleton

36.4 kDa (305aa) confirmed by MALDI-TOF

MSDIEEVVEE YEEEEQEEAA VEEQEEAAEE DAEAEAETEE TRAEEDEEEE EAKEAEDGPM EESKPKPRSF MPNLVPPKIP DGERVDFDDI HRKRMEKDLN ELQALIEAHF ENRKKEEEEL VSLKDRIERR RAERAEQQRI RNEREKERQN RLAEERARRE EEENRRKAED EARKKKALSN MMHFGGYIQK TERKSGKRQT EREKKKKILA ERRKVLAIDH LNEDQLREKA KELWQSIYNL EAEKFDLQEK FKQQKYEINV LRNRINDNQK VSKTRGKAKV TGRWK

His-Tag

E.coli

Recombinant Protein

P45379

Troponin T, Troponin T type 2 cardiac isoform 3, Troponin T type 2, cardiac isoform 3, CMH2, CMPD2, cTnT, RCM3, TnTC, Troponin T type 2, cardiac isoform 3 Cardiac muscle troponin T, MGC3889, TNNT 2, TNNT2, Cardiomyopathy hypertrophic 2, Cardiomyopathy dilated 1D (autosomal dominant), CMD1D, Troponin T cardiac muscle, Troponin T type 2 (cardiac), Troponin T type 2 cardiac, Troponin T2 cardiac,ATGP0329-100,ATGP0329-10ug,ATGP0329-20ug,ATGP0329-50ug,ATGP0329-100ug,ATGP0329-250ug,ATGP0329-500ug,ATGP0329-1mg,ATGP0329-10,ATGP0329-20,ATGP0329-50,ATGP0329-100,ATGP0329-250,ATGP0329-500,ATGP0329-1