Recombinant human BMF protein | NKMAX ATGP0324 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human BMF protein

catalog :

ATGP0324

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human BMF protein

Domain :

1-129aa

Catalog number (SKU) :

ATGP0324

NCBI :

NP_001003943

Description :

Bcl2 modifying factor, also known as BMF belongs to the Bcl2 protein family of apoptosis mediators. Bmf is constitutively expressed in many tissues. This protein contains a single Bcl2 homology domain 3 (BH3), and has been shown to bind Bcl2 proteins and function as an apoptotic activator. Also, BMF is a key molecule for histone deacetylase (HDAC) inhibitors which alters the balance between acetylation and deacetylation, significantly increasing histone acetylation, while strongly inducing apoptosis in a variety of cancer cell types. Recombinant human BMF, fused to T7-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

Bcl2 modifying factor isoform 3, Bcl2 modifying factor, isoform 3, BMF, Bcl2 modifying factor, isoform 3 Bcl 2 modifying factor, FLJ00065.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing, 1mM DTT, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Morales AA., et al. (2004). Leukemia. 18(1):41-7;; Chen L., et al. (2005). Mol Cell. 17(3):393-403;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

15.6 kDa (144aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MASMTGGQQM GRGSHMEPSQ CVEELEDDVF QPEDGEPVTQ PGSLLSADLF AQSLLDCPLS RLQLFPLTHC CGPGLRPTSQ EDKATQTLSP ASPSQGVMLP CGVTEEPQRL FYAPAEPKSC VVADPPLPAQ PCFEWRREQE RGRP

Tag :

T7-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q96LC9

Internal Search Terms :

BMF, Bcl2 modifying factor isoform 3, Bcl2 modifying factor, isoform 3, BMF, Bcl2 modifying factor, isoform 3 Bcl 2 modifying factor, FLJ00065.,ATGP0324-10ug,ATGP0324-20ug,ATGP0324-50ug,ATGP0324-100ug,ATGP0324-250ug,ATGP0324-500ug,ATGP0324-1mg,ATGP0324-10,ATGP0324-20,ATGP0324-50,ATGP0324-100,ATGP0324-250,ATGP0324-500,ATGP0324-1

more info or order :

NKMAX product webpage