Recombinant mouse IFN-beta 1/IFNB1 protein | NKMAX ATGP0317 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse IFN-beta 1/IFNB1 protein

catalog :

ATGP0317

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse IFN-beta 1/IFNB1 protein

Domain :

22-182aa

Catalog number (SKU) :

ATGP0317

NCBI :

NP_034640.1

Description :

Interferon beta 1, also known as IFN-beta, is produced mainly by fibroblasts and some epithelial cell types. IFN-beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. It also increases the expression of HLA class I antigens and blocks the expression of HLA class II antigens stimulated by IFN-gamma. Interferon beta 1 can be used for topic treatment of condylomata acuminata. Some studies suggest that Interferon beta 1 tends to prevent disease activity in patients with multiple sclerosis. Recombinant Interferon beta 1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Ifb, IFN-beta, IFNB, Interferon beta 1, Interferon beta, Fibroblast interferon

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM HEPES buffer (pH 6.0) containing 0.5M NaCl, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Fierlbeck G, et al. (1992) Hautarzt. 43(1):16-21. ;; Panitch HS. (1992) Drugs. 44(6):946-62.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Mouse

Gene Category :

Hormones & Cytokines

Molecular Weight :

22.0 kDa (182aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

INYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P01575

Internal Search Terms :

IFN-b, Ifb, IFN-beta, IFNB, Interferon beta 1,ATGP0317-10ug,ATGP0317-20ug,ATGP0317-50ug,ATGP0317-100ug,ATGP0317-250ug,ATGP0317-500ug,ATGP0317-1mg,ATGP0317-10,ATGP0317-20,ATGP0317-50,ATGP0317-100,ATGP0317-250,ATGP0317-500,ATGP0317-1

References with this Product :

Okumura F, et al. Activation of double-stranded RNA-activated protein kinase (PKR) by interferon-stimulated gene 15 (ISG15) modification down-regulates protein translation. (J Biol Chem. 2013){https://www.ncbi.nlm.nih.gov/pubmed/23229543}

more info or order :

NKMAX product webpage