Recombinant human TANK protein | NKMAX ATGP0306 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TANK protein

catalog :

ATGP0306

quantity :

20 ug

price :

70 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TANK protein

Domain :

1-119aa

Catalog number (SKU) :

ATGP0306

NCBI :

NP_597841

Description :

TANK, also known as TRAF (tumor necrosis factor receptor-associated Factor) -interacting protein, is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby proposing that this protein is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1. Recombinant human TANK protein was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

TRAF interacting protein TANK isoform b, TRAF interacting protein TANK isoform b, I-TRAF, TRAF2, TRAF interacting protein TANK isoform b I TRAF, ITRAF, TRAF interacting protein, TRAF family member associated NF KAPPA B activator, TRAF family member associated NFKB activator, TRAF interacting protein TANK isoform a

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0)

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Rothe M., et al. (1996) Proc Natl Acad Sci u S A. 93(16):8241-6.;; Gatot JS., et al. (2007) J Biol Chem. 282(43):31131-46.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

13.6 kDa (119aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV DIASAESSI

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q92844

Internal Search Terms :

TANK, TRAF interacting protein TANK isoform b, TRAF interacting protein TANK isoform b, I-TRAF, TRAF2, TRAF interacting protein TANK isoform b I TRAF, ITRAF, TRAF interacting protein, TRAF family member associated NF KAPPA B activator, TRAF family member associated NFKB activator, TRAF interacting protein TANK isoform a,ATGP0306-10ug,ATGP0306-20ug,ATGP0306-50ug,ATGP0306-100ug,ATGP0306-250ug,ATGP0306-500ug,ATGP0306-1mg,ATGP0306-10,ATGP0306-20,ATGP0306-50,ATGP0306-100,ATGP0306-250,ATGP0306-500,ATGP0306-1

more info or order :

NKMAX product webpage