Recombinant human SPG21 protein | NKMAX ATGP0287 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human SPG21 protein

catalog :

ATGP0287

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human SPG21 protein

Domain :

1-308aa

Catalog number (SKU) :

ATGP0287

NCBI :

NP_057714

Description :

Spastic paraplegia 21 (SPG21), also known as Maspardin, binds to the hydrophobic C-terminal amino acids of CD4 and may play a role as a negative regulatory factor in CD4-depenent T-cell activation. This protein is widely expressed in various tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Mutations in SPG21 cause Mast syndrome, an autosomal-recessive complicated form of hereditary spastic paraplegia characterized by dementia, thin corpus callosum and white matter abnormalities. Recombinant human SPG21 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

Spastic paraplegia 21 isoform a, ACP33, BM-019, GL010, Maspardin, MAST, Spastic paraplegia 21 isoform a Acid cluster protein 33, BM019, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, SPG21.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0)

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Simpson MA., et al. (2003). Am J Hum Genet. 73(5):1147-56.;; Zeitlmann L., et al. (2001). J Biol Chem. 276(12):9123-32.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

37.1 kDa (328aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGEIKVSPDY NWFRGTVPLK KIIVDDDDSK IWSLYDAGPR SIRCPLIFLP PVSGTADVFF RQILALTGWG YRVIALQYPV YWDHLEFCDG FRKLLDHLQL DKVHLFGASL GGFLAQKFAE YTHKSPRVHS LILCNSFSDT SIFNQTWTAN SFWLMPAFML KKIVLGNFSS GPVDPMMADA IDFMVDRLES LGQSELASRL TLNCQNSYVE PHKIRDIPVT IMDVFDQSAL STEAKEEMYK LYPNARRAHL KTGGNFPYLC RSAEVNLYVQ IHLLQFHGTK YAAIDPSMVS AEELEVQKGS LGISQEEQ

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9NZD8

Internal Search Terms :

SPG21, Spastic paraplegia 21 isoform a, ACP33, BM-019, GL010, Maspardin, MAST, Spastic paraplegia 21 isoform a Acid cluster protein 33, BM019, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, SPG21.,ATGP0287-10ug,ATGP0287-20ug,ATGP0287-50ug,ATGP0287-100ug,ATGP0287-250ug,ATGP0287-500ug,ATGP0287-1mg,ATGP0287-10,ATGP0287-20,ATGP0287-50,ATGP0287-100,ATGP0287-250,ATGP0287-500,ATGP0287-1

more info or order :

NKMAX product webpage