Recombinant human GRB2 protein | NKMAX ATGP0286 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human GRB2 protein

catalog :

ATGP0286

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human GRB2 protein

Domain :

1-217aa

Catalog number (SKU) :

ATGP0286

NCBI :

NP_002077.1

Description :

Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. GRB2 is widely expressed and also binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Grb2 is composed of an SH2 domain flanked on each side by an SH3 domain. Inhibition of Grb2 function impairs developmental processes in various organisms and blocks transformation and proliferation of various cell types. Recombinant human GRB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

Growth factor receptor-bound protein 2 isoform 1, Growth factor receptor-bound protein 2 isoform 1, ASH, EGFRBP-GRB2, GRB3-3, Growth factor receptor-bound protein 2 isoform 1 Abundant SRC homology, Adapter protein GRB2, Ash protein, EGFRBP GRB2, Epidermal growth factor receptor binding protein, Epidermal growth factor receptor binding protein GRB2, GRB 2, GRB2 adapter protein, Grb3 3, Growth factor receptor bound protein 2, Growth factor receptor bound protein 3, HT027, MST084, MSTP084, OTTHuMP00000166096, OTTHuMP00000166097, OTTHuMP00000166098, Protein ASH, SEM5, SH2/SH3 adapter GRB2.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Rudd CE., et al. (2009) Immunol Rev. 229(1):12-26.;; Weisswange I., et al. (2009) Nature. 458(7234):87-91.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

27 kDa (237aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK NYIEMKPHPW FFGKIPRAKA EEMLSKQRHD GAFLIRESES APGDFSLSVK FGNDVQHFKV LRDGAGKYFL WVVKFNSLNE LVDYHRSTSV SRNQQIFLRD IEQVPQQPTY VQALFDFDPQ EDGELGFRRG DFIHVMDNSD PNWWKGACHG QTGMFPRNYV TPVNRNV

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P62993

Internal Search Terms :

GRB2, Growth factor receptor-bound protein 2 isoform 1, Growth factor receptor-bound protein 2 isoform 1, ASH, EGFRBP-GRB2, GRB3-3, Growth factor receptor-bound protein 2 isoform 1 Abundant SRC homology, Adapter protein GRB2, Ash protein, EGFRBP GRB2, Epidermal growth factor receptor binding protein, Epidermal growth factor receptor binding protein GRB2, GRB 2, GRB2 adapter protein, Grb3 3, Growth factor receptor bound protein 2, Growth factor receptor bound protein 3, HT027, MST084, MSTP084, OTTHuMP00000166096, OTTHuMP00000166097, OTTHuMP00000166098, Protein ASH, SEM5, SH2/SH3 adapter GRB2.,ATGP0286-10ug,ATGP0286-20ug,ATGP0286-50ug,ATGP0286-100ug,ATGP0286-250ug,ATGP0286-500ug,ATGP0286-1mg,ATGP0286-10,ATGP0286-20,ATGP0286-50,ATGP0286-100,ATGP0286-250,ATGP0286-500,ATGP0286-1

more info or order :

NKMAX product webpage