protein

Recombinant human Peroxiredoxin 2/PRDX2 protein

ATGP0268

20 ug

105 USD

Recombinant human Peroxiredoxin 2/PRDX2 protein

1-198aa

ATGP0268

NP_005800.3

Peroxiredoxin 2, also known as PRDX2, is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Peroxiredoxin 2 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8 (+) T-cells. If Peroxiredoxin 2 protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. Recombinant human Peroxiredoxin 2 protein was expressed in E. coli and purified by using conventional chromatography.

Peroxiredoxin 2, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA, PRDX2, Peroxiredoxin 2, MGC4104, Natural killer cell enhancing factor B, Natural Killer Enhancing Factor B, NKEF B, PRDX 2, TDPX1, Thiol Specific Antioxidant 1, Thiol specific antioxidant protein, Thioredoxin Dependent Peroxide Reductase 1, Thioredoxin Peroxidase 1, Torin.

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Kim K., et al. (2009), Oncol Rep, 21(6):1391-6.;; Kim JH., et al. (2008). Clin Cancer Res. 14(8):2326-33.;;

> 90% by SDS-PAGE

Specific activity is >2,000pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for minute.

SDS-PAGE, Enzyme Activity

Human

Redox Proteins

21.8 kDa (198aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

Specific activity is >2,000 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25C for minute.

MASGNARIGK PAPDFKATAV VDGAFKEVKL SDYKGKYVVL FFYPLDFTFV CPTEIIAFSN RAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTRR LSEDYGVLKT DEGIAYRGLF IIDGKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS DTIKPNVDDS KEYFSKHN

Non-Tagged

E.coli

Recombinant Protein

P32119

Peroxiredoxin2, PRDX2, Peroxiredoxin 2, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA, PRDX2, Peroxiredoxin 2, MGC4104, Natural killer cell enhancing factor B, Natural Killer Enhancing Factor B, NKEF B, PRDX 2, TDPX1, Thiol Specific Antioxidant 1, Thiol specific antioxidant protein, Thioredoxin Dependent Peroxide Reductase 1, Thioredoxin Peroxidase 1, Torin.,ATGP0268-10ug,ATGP0268-20ug,ATGP0268-50ug,ATGP0268-100ug,ATGP0268-250ug,ATGP0268-500ug,ATGP0268-1mg,ATGP0268-10,ATGP0268-20,ATGP0268-50,ATGP0268-100,ATGP0268-250,ATGP0268-500,ATGP0268-1

Ogasawara Y, et al. A simple high performance liquid chromatography method for quantitatively determining the reduced form of peroxiredoxin 2 and the mass spectrometric analysis of its oxidative status. (J Chromatogr B Analyt Technol Biomed Life Sci. 2015){https://pubmed.ncbi.nlm.nih.gov/26113455/}