product summary
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company name :
NKMAX
product type :
cDNA
product name :
RNASEH2A cDNA
catalog :
ATGD0491
quantity :
10 ug
price :
99 USD
more info or order :
NKMAX product webpage
product information
Product Type :
cDNAs
Item Name :
RNASEH2A cDNA
Catalog number (SKU) :
ATGD0491
NCBI :
NP_006388.2
Description :
RNASEH2A is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.
Alternative Names :
AGS4, JUNB, RNASEHI, RNHIA, RNHL
Formulation :
Lyophilized
Storage :
Store the plasmid at -20C.
Antigen Species :
Human
Gene Category :
Epigenomics (Transcription & Translation)
Nucleotide Sequence :
ATGGATCTCAGCGAGCTGGAGAGAGACAATACAGGCCGC
TGTCGCCTGAGTTCGCCTGTGCCCGCGGTGTGCCGCAAG
GAGCCTTGCGTCCTGGGCGTCGATGAGGCGGGCAGGGGC
CCCGTGCTGGGCCCCATGGTCTACGCCATCTGTTATTGT
CCCCTGCCTCGCCTGGCAGATCTGGAGGCGCTGAAAGTG
GCAGACTCAAAGACCCTATTGGAGAGCGAGCGGGAAAGG
CTGTTTGCGAAAATGGAGGACACGGACTTTGTCGGCTGG
GCGCTGGATGTGCTGTCTCCAAACCTCATCTCTACCAGC
ATGCTTGGGCGGGTCAAATACAACCTGAACTCCCTGTCA
CATGATACAGCCACTGGGCTTATACAGTATGCATTGGAC
CAGGGCGTGAACGTCACCCAGGTATTCGTGGACACCGTA
GGGATGCCAGAGACATACCAGGCGCGGCTGCAGCAAAGT
TTTCCCGGGATTGAGGTGACGGTCAAGGCCAAAGCAGAT
GCCCTCTACCCGGTGGTTAGTGCTGCCAGCATCTGTGCC
AAGGTGGCCCGGGACCAGGCCGTGAAGAAATGGCAGTTC
GTGGAGAAACTGCAGGACTTGGATACTGATTATGGCTCA
GGCTACCCCAATGATCCCAAGACAAAAGCGTGGTTGAAG
GAGCACGTGGAGCCTGTGTTCGGCTTCCCCCAGTTTGTC
CGGTTCAGCTGGCGCACGGCCCAGACCATCCTGGAGAAA
GAGGCGGAAGATGTTATATGGGAGGACTCAGCATCCGAG
AATCAGGAGGGACTCAGGAAGATCACATCCTACTTCCTC
AATGAAGGGTCCCAAGCCCGTCCCCGTTCTTCCCACCGA
TATTTCCTGGAACGCGGCCTGGAGTCAGCAACCAGCCTC
TAG
Translation Sequence :
MDLSELERDN TGRCRLSSPV PAVCRKEPCV LGVDEAGRGP VLGPMVYAIC YCPLPRLADLEALKVADSKT LLESERERLF AKMEDTDFVG WALDVLSPNL ISTSMLGRVK YNLNSLSHDTATGLIQYALD QGVNVTQVFV DTVGMPETYQ ARLQQSFPGI EVTVKAKADA LYPVVSAASICAKVARDQAV KKWQFVEKLQ DLDTDYGSGY PNDPKTKAWL KEHVEPVFGF PQFVRFSWRTAQTILEKEAE DVIWEDSASE NQEGLRKITS YFLNEGSQAR PRSSHRYFLE RGLESATSL
RNA Reference Number :
NM_006397.2
OMIM Number :
606034
Chromosome Location :
19p13.2
DNA size :
900bp
Preparation before usage :
1. Centrifuge at 7000rpm for 1 minute.;;2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.;;Each tube contains approximately 10ug of lyophilized plasmid.
Vector :
pATGen (puc19-derived cloning vector)
Vector description :
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Product Type Name :
cDNA
Internal Search Terms :
RNASEH2A, AGS4, JUNB, RNASEHI, RNHIA, RNHL, RNASEH2A,ATGD0491-10ug,ATGD0491-20ug,ATGD0491-50ug,ATGD0491-100ug,ATGD0491-250ug,ATGD0491-500ug,ATGD0491-1mg,ATGD0491-10,ATGD0491-20,ATGD0491-50,ATGD0491-100,ATGD0491-250,ATGD0491-500,ATGD0491-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.