product summary
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company name :
NKMAX
product type :
cDNA
product name :
CPSF4 cDNA
catalog :
ATGD0259
quantity :
10 ug
price :
99 USD
more info or order :
NKMAX product webpage
product information
Product Type :
cDNAs
Item Name :
CPSF4 cDNA
Catalog number (SKU) :
ATGD0259
NCBI :
NP_001075028.1
Description :
Inhibition of the nuclear export of poly (A) -containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for CPSF4.
Alternative Names :
CPSF30, NAR, NEB1
Formulation :
Lyophilized
Storage :
Store the plasmid at -20C.
Antigen Species :
Human
Gene Category :
Epigenomics (Transcription & Translation)
Nucleotide Sequence :
ATGCAGGAAATCATCGCCAGCGTGGACCACATCAAGTTT
GACTTGGAGATCGCGGTGGAGCAGCAGCTGGGGGCGCAG
CCGCTGCCCTTCCCCGGCATGGACAAGTCGGGCGCTGCT
GTCTGTGAATTCTTTTTGAAAGCTGCCTGCGGCAAAGGG
GGCATGTGTCCGTTTCGCCACATCAGTGGTGAGAAGACA
GTTGTGTGCAAACACTGGCTGCGTGGCCTATGCAAGAAA
GGGGACCAGTGTGAGTTCCTGCATGAGTATGACATGACC
AAGATGCCCGAGTGCTACTTCTACTCCAAGTTCGGGGAG
TGCAGCAACAAGGAATGTCCCTTCCTGCACATCGACCCC
GAGTCCAAGATCAAGGACTGTCCTTGGTATGACCGTGGC
TTCTGCAAGCACGGTCCCCTCTGCAGGCACCGGCACACA
CGGAGAGTCATCTGTGTGAATTACCTCGTGGGATTCTGC
CCGGAGGGGCCCTCGTGTAAATTCATGCACCCTCGATTT
GAACTGCCCATGGGAACCACCGAGCAGCCCCCACTGCCG
CAGCAGACACAGCCTCCAGCAAAGCAGAGAACCCCGCAG
GTCATCGGGGTCATGCAGAGTCAAAACAGCAGCGCGGGC
AACCGGGGACCCCGGCCACTGGAGCAGGTCACCTGTTAC
AAGTGTGGCGAGAAAGGACACTACGCCAACAGATGCACC
AAAGGGCACTTGGCCTTTCTCAGTGGACAGTGA
Translation Sequence :
MQEIIASVDH IKFDLEIAVE QQLGAQPLPF PGMDKSGAAV CEFFLKAACG KGGMCPFRHISGEKTVVCKH WLRGLCKKGD QCEFLHEYDM TKMPECYFYS KFGECSNKEC PFLHIDPESKIKDCPWYDRG FCKHGPLCRH RHTRRVICVN YLVGFCPEGP SCKFMHPRFE LPMGTTEQPPLPQQTQPPAK QRTPQVIGVM QSQNSSAGNR GPRPLEQVTC YKCGEKGHYA NRCTKGHLAFLSGQ
RNA Reference Number :
NM_001081559.1
OMIM Number :
603052
Chromosome Location :
7q22.1
DNA size :
735bp
Preparation before usage :
1. Centrifuge at 7000rpm for 1 minute.;;2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.;;Each tube contains approximately 10ug of lyophilized plasmid.
Vector :
pATGen (puc19-derived cloning vector)
Vector description :
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Product Type Name :
cDNA
Internal Search Terms :
CPSF4, CPSF30, NAR, NEB1, CPSF4,ATGD0259-10ug,ATGD0259-20ug,ATGD0259-50ug,ATGD0259-100ug,ATGD0259-250ug,ATGD0259-500ug,ATGD0259-1mg,ATGD0259-10,ATGD0259-20,ATGD0259-50,ATGD0259-100,ATGD0259-250,ATGD0259-500,ATGD0259-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.