STRADA cDNA | NKMAX ATGD0156 product information

product summary

company name :

NKMAX

product type :

cDNA

product name :

STRADA cDNA

catalog :

ATGD0156

quantity :

10 ug

price :

99 USD

more info or order :

NKMAX product webpage

product information

Product Type :

cDNAs

Item Name :

STRADA cDNA

Catalog number (SKU) :

ATGD0156

NCBI :

NP_001159441.1

Description :

STRADA encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. STRADA forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). STRADA activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. STRADA is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.

Alternative Names :

LYK5, NY-BR-96, PMSE, Stlk, STRAD

Formulation :

Lyophilized

Storage :

Store the plasmid at -20C.

Antigen Species :

Human

Gene Category :

Cell Cycle

Nucleotide Sequence :

ATGTCATTTCTTGTAAGTAAACCAGAGCGAATCAGGACC
AATGATGCGAGCTCAGAGTCAATAGCATCCTTCTCTAAA
CAGGAGGTCATGAGTAGCTTTCTGCCAGAGGGAGGGTGT
TACGAGCTGCTCACTGTGATAGGCAAAGGATTTGAGGAC
CTGATGACTGTGAATCTAGCAAGGTACAAACCAACAGGA
GAGTACGTGACTGTACGGAGGATTAACCTAGAAGCTTGT
TCCAATGAGATGGTAACATTCTTGCAGGGCGAGCTGCAT
GTCTCCAAACTCTTCAACCATCCCAATATCGTGCCATAT
CGAGCCACTTTTATTGCAGACAATGAGCTGTGGGTTGTC
ACATCATTCATGGCATACGGTTCTGCAAAAGATCTCATC
TGTACACACTTCATGGATGGCATGAATGAGCTGGCGATT
GCTTACATCCTGCAGGGGGTGCTGAAGGCCCTCGACTAC
ATCCACCACATGGGATATGTACACAGGAGTGTCAAAGCC
AGCCACATCCTGATCTCTGTGGATGGGAAGGTCTACCTG
TCTGGTTTGCGCAGCAACCTCAGCATGATAAGCCATGGG
CAGCGGCAGCGAGTGGTCCACGATTTTCCCAAGTACAGT
GTCAAGGTTCTGCCGTGGCTCAGCCCCGAGGTCCTCCAG
CAGAATCTCCAGGGTTATGATGCCAAGTCTGACATCTAC
AGTGTGGGAATCACAGCCTGTGAACTGGCCAACGGCCAT
GTCCCCTTTAAGGATATGCCTGCCACCCAGATGCTGCTA
GAGAAACTGAACGGCACAGTGCCCTGCCTGTTGGATACC
AGCACCATCCCCGCTGAGGAGCTGACCATGAGCCCTTCG
CGCTCAGTGGCCAACTCTGGCCTGAGTGACAGCCTGACC
ACCAGCACCCCCCGGCCCTCCAACGGCCCAGTGCCAGCA
CCCTCCTGA

Translation Sequence :

MSFLVSKPER IRTNDASSES IASFSKQEVM SSFLPEGGCY ELLTVIGKGF EDLMTVNLARYKPTGEYVTV RRINLEACSN EMVTFLQGEL HVSKLFNHPN IVPYRATFIA DNELWVVTSFMAYGSAKDLI CTHFMDGMNE LAIAYILQGV LKALDYIHHM GYVHRSVKAS HILISVDGKVYLSGLRSNLS MISHGQRQRV VHDFPKYSVK VLPWLSPEVL QQNLQGYDAK SDIYSVGITACELANGHVPF KDMPATQMLL EKLNGTVPCL LDTSTIPAEE LTMSPSRSVA NSGLSDSLTTSTPRPSNGPV PAPS

RNA Reference Number :

NM_001165969.1

OMIM Number :

608626

Chromosome Location :

17q23.3

DNA size :

945bp

Preparation before usage :

1. Centrifuge at 7000rpm for 1 minute.;;2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.;;Each tube contains approximately 10ug of lyophilized plasmid.

Vector :

pATGen (puc19-derived cloning vector)

Vector description :

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

Product Type Name :

cDNA

Internal Search Terms :

STRADA, LYK5, NY-BR-96, PMSE, Stlk, STRAD, STRADA,ATGD0156-10ug,ATGD0156-20ug,ATGD0156-50ug,ATGD0156-100ug,ATGD0156-250ug,ATGD0156-500ug,ATGD0156-1mg,ATGD0156-10,ATGD0156-20,ATGD0156-50,ATGD0156-100,ATGD0156-250,ATGD0156-500,ATGD0156-1

more info or order :

NKMAX product webpage