RPA2 cDNA | NKMAX ATGD0142 product information

product summary

company name :

NKMAX

product type :

cDNA

product name :

RPA2 cDNA

catalog :

ATGD0142

quantity :

10 ug

price :

99 USD

more info or order :

NKMAX product webpage

product information

Product Type :

cDNAs

Item Name :

RPA2 cDNA

Catalog number (SKU) :

ATGD0142

NCBI :

NP_002937.1

Description :

As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, RPA2 plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. RPA2 is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage. Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair.

Alternative Names :

REPA2, RP-A p32, RP-A p34, RPA32

Formulation :

Lyophilized

Storage :

Store the plasmid at -20C.

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Nucleotide Sequence :

ATGTGGAACAGTGGATTCGAAAGCTATGGCAGCTCCTCA
TACGGGGGAGCCGGCGGCTACACGCAGTCCCCGGGGGGC
TTTGGATCGCCCGCACCTTCTCAAGCCGAAAAGAAATCA
AGAGCCCGAGCCCAGCACATTGTGCCCTGTACTATATCT
CAGCTGCTTTCTGCCACTTTGGTTGATGAAGTGTTCAGA
ATTGGGAATGTTGAGATTTCACAGGTCACTATTGTGGGG
ATCATCAGACATGCAGAGAAGGCTCCAACCAACATTGTT
TACAAAATAGATGACATGACAGCTGCACCCATGGACGTT
CGCCAGTGGGTTGACACAGATGACACCAGCAGTGAAAAC
ACTGTGGTTCCTCCAGAAACATATGTGAAAGTGGCAGGC
CACCTGAGATCTTTTCAGAACAAAAAGAGCCTGGTAGCC
TTTAAGATCATGCCCCTGGAGGATATGAATGAGTTCACC
ACACATATTCTGGAAGTGATCAATGCACACATGGTACTA
AGCAAAGCCAACAGCCAGCCCTCAGCAGGGAGAGCACCT
ATCAGCAATCCAGGAATGAGTGAAGCAGGGAACTTTGGT
GGGAATAGCTTCATGCCAGCAAATGGCCTCACTGTGGCC
CAAAACCAGGTGTTGAATTTGATTAAGGCTTGTCCAAGA
CCTGAAGGGTTGAACTTTCAGGATCTCAAGAACCAGCTG
AAACACATGTCTGTATCCTCAATCAAGCAAGCTGTGGAT
TTTCTGAGCAATGAGGGGCACATCTATTCTACTGTGGAT
GATGACCATTTTAAATCCACAGATGCAGAATAA

Translation Sequence :

MWNSGFESYG SSSYGGAGGY TQSPGGFGSP APSQAEKKSR ARAQHIVPCT ISQLLSATLVDEVFRIGNVE ISQVTIVGII RHAEKAPTNI VYKIDDMTAA PMDVRQWVDT DDTSSENTVVPPETYVKVAG HLRSFQNKKS LVAFKIMPLE DMNEFTTHIL EVINAHMVLS KANSQPSAGRAPISNPGMSE AGNFGGNSFM PANGLTVAQN QVLNLIKACP RPEGLNFQDL KNQLKHMSVSSIKQAVDFLS NEGHIYSTVD DDHFKSTDAE

RNA Reference Number :

NM_002946.4

OMIM Number :

179836

Chromosome Location :

1p35

DNA size :

813bp

Preparation before usage :

1. Centrifuge at 7000rpm for 1 minute.;;2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.;;Each tube contains approximately 10ug of lyophilized plasmid.

Vector :

pATGen (puc19-derived cloning vector)

Vector description :

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

Product Type Name :

cDNA

Internal Search Terms :

RPA2, REPA2, RP-A p32, RP-A p34, RPA32, RPA2,ATGD0142-10ug,ATGD0142-20ug,ATGD0142-50ug,ATGD0142-100ug,ATGD0142-250ug,ATGD0142-500ug,ATGD0142-1mg,ATGD0142-10,ATGD0142-20,ATGD0142-50,ATGD0142-100,ATGD0142-250,ATGD0142-500,ATGD0142-1

more info or order :

NKMAX product webpage