Human KAT2A/GCN5 antibody | NKMAX ATGA0527 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human KAT2A/GCN5 antibody

catalog :

ATGA0527

quantity :

50 ul

price :

190 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT3G13

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human KAT2A/GCN5 antibody

Catalog number (SKU) :

ATGA0527

NCBI :

NP_066564

Description :

GCN5L2, as known as GCN5 and KAT2A is the use of immunoprecipitated GCN5L2 for acetylation toprovide the additional components important for acetylation. GCN5L2 can be one of the potential enzymesinvolved in acetylation in vivo. GCN5L2 is expressed predominantly in the embryo and newborn and is essentialfor normal embryonic development. Therefore, GCN5L2 appears to be important for differentiation ofembryonic-derived preadipocytes. On the one hand, loss of GCN5L2 leads to high incidence of apoptosis inthe GCN5L2 mutants that begins before the onset of morphological abnormality.

Alternative Names :

STAF97, PCAF-b, Lysine acetyltransferase 2A, Histone succinyltransferase KAT2A, Histone glutaryltransferase KAT2A, Histone acetyltransferase KAT2A, Histone acetyltransferase GCN5, General control of amino-acid synthesis 5-like 2, General control of amino acid synthesis protein 5-like 2, GCN5L2, GCN5

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wiper-Bergeron N, et al. (2007) Proc Natl Acad Sci U S A, 104(8):2703-8.;;Jacob AL, et al. (2001) J Biol Chem, 276(40):37659-64.;;Xu W, et al. (2000) Nat Genet, 26(2):229-232.

Abs Host :

Mouse

Isotype :

IgG2a kappa

Immunogen :

Recombinant human GCN5L2 (411-837aa) purified from E. coli

Applications :

ELISA, WB, ICC/IF

IF Comment And Pic :

ICC/IF analysis of GCN5L2 in HeLa cells. The cell was stained with ATGA0527 (1:500). The secondary antibody (green) was used Alexa Fluor 488.

WB Comment and Pic :

The cell lysate(35ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human GCN5L2 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;;Lane 1.: HeLa cell lysate;;

Reacts With :

Human

Clone Number :

AT3G13

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results

Antigen Species :

Human

Gene Category :

Epigenetics and Nuclear Signaling

Additional Comment Only :

This product was produced from tissue culture supernatant.

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal antibody

UniProt No. :

Q92830

Internal Search Terms :

STAF97, PCAF-b, Lysine acetyltransferase 2A, KAT2A, K(lysine) acetyltransferase 2A, Histone succinyltransferase KAT2A, Histone glutaryltransferase KAT2A, Histone acetyltransferase KAT2A, Histone acetyltransferase GCN5, hGCN5L2, hGCN5, General control of amino-acid synthesis 5-like 2, General control of amino acid synthesis protein 5-like 2, GCN5L2, GCN5, ATGA0527-10ug, ATGA0527-20ug, ATGA0527-50ug, ATGA0527-100ug, ATGA0527-250ug, ATGA0527-500ug, ATGA0527-1mg, ATGA0527-010, ATGA0527-020, ATGA0527-050, ATGA0527-100, ATGA0527-250, ATGA0527-500, ATGA0527-01M

more info or order :

NKMAX product webpage