Human NMNAT-1 antibody | NKMAX ATGA0516 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human NMNAT-1 antibody

catalog :

ATGA0516

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT4G8

reactivity :

human

application :

western blot, ELISA

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human NMNAT-1 antibody

Catalog number (SKU) :

ATGA0516

NCBI :

NP_073624

Description :

NMNAT1, also known as NMNAT or PNAT1, is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD. It is widely expressed with high levels in skeletal muscle, heart, liver and kidney. This protein appears to have the ability to protect against axonal degeneration following mechanical or toxic insults.

Alternative Names :

Nicotinamide nucleotide adenylyltransferase 1, Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1, NMN/NaMN adenylyltransferase 1, Nicotinamide nucleotide adenylyltransferase, Leber's congenital amaurosis 9, LCA9, PNAT1, NMNAT

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Emanuelli M. et al. (2001) J Biol Chem. 276(1):406-12.;;Zhou T,.,et al. (2002) J Biol Chem. 277(15):13148-54.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human NMNAT1 (19-609aa) purified from E. coli

Applications :

ELISA, WB

WB Comment and Pic :

The cell lysates were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NMNAT-1 antibody (1:2000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;;Lane 1.: 293T cell lysate (40ug);;Lane 2.: NMNAT1 transfected 293T cell lysate (10ug)

Reacts With :

Human

Clone Number :

AT4G8

Ab Usage :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Neuroscience

Additional Comment Only :

ATGA0186 has been replaced with a catalog number ATGA0516.

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q9HAN9

Internal Search Terms :

PNAT1, PNAT 1, NMNAT1, NMNAT 1, NMNAT, NMN/NaMN adenylyltransferase1, NMN/NaMN adenylyltransferase 1, Nicotinamide/nicotinic acid mononucleotide adenylyltransferase1, Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1, Nicotinamide nucleotide adenylyltransferase1, Nicotinamide nucleotide adenylyltransferase 1, Nicotinamide nucleotide adenylyltransferase, Leber's congenital amaurosis 9, LCA9, ATGA0516-10ug, ATGA0516-20ug, ATGA0516-50ug, ATGA0516-100ug, ATGA0516-250ug, ATGA0516-500ug, ATGA0516-1mg, ATGA0516-010, ATGA0516-020, ATGA0516-050, ATGA0516-100, ATGA0516-250, ATGA0516-500, ATGA0516-01M

more info or order :

NKMAX product webpage