Human TRAILR3/TNFRSF10C antibody | NKMAX ATGA0509 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human TRAILR3/TNFRSF10C antibody

catalog :

ATGA0509

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT1E12

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human TRAILR3/TNFRSF10C antibody

Catalog number (SKU) :

ATGA0509

NCBI :

NP_003832

Description :

TNFRSF10C also known as tumor necrosis factor receptor superfamily member 10C is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis.

Alternative Names :

Tumor necrosis factor receptor superfamily member 10C, Antagonist decoy receptor for TRAIL/Apo-2L, Decoy TRAIL receptor without death domain, Decoy receptor 1, DcR1, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TRAIL receptor 3, TRAIL-R3, CD263, LIT, TRAILR3, TRID, TRAIL receptor without an intracellular domain

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Venza M., et al. (2013) Biochem. Biophys. Res. Commun. 441 (4), 743-750.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human TNFRSF10C (26-236aa) purified from E. coli

Applications :

ELISA, WB, ICC/IF

IF Comment And Pic :

ICC/IF analysis of TNFRSF10C in HeLa cells. The cell was stained with ATGA0509 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The tissue lysate (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human TNFRFS10C antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;; Lane 1.: Mouse Liver tissue lysate

Reacts With :

Human

Clone Number :

AT1E12

Ab Usage :

The antibody has been tested by ELISA, Western blot analysis and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Apoptosis

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

O14798

Internal Search Terms :

TRAIL R3, TNFRSF10C,ATGA0509-10ug,ATGA0509-20ug,ATGA0509-50ug,ATGA0509-100ug,ATGA0509-250ug,ATGA0509-500ug,ATGA0509-1mg,ATGA0509-10,ATGA0509-20,ATGA0509-50,ATGA0509-100,ATGA0509-250,ATGA0509-500,ATGA0509-1

more info or order :

NKMAX product webpage