Human XPA antibody | NKMAX ATGA0502 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human XPA antibody

catalog :

ATGA0502

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT71H3

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human XPA antibody

Catalog number (SKU) :

ATGA0502

NCBI :

NP_000371

Description :

XPA, also known as DNA repair protein complementing XP-A cells, belong to the XPA family. This protein is involved in DNA excision repair. It Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Defects in XPA are a cause of xeroderma pigmentosum complementation group A (XP-A), which is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities.

Alternative Names :

DNA repair protein complementing XP-A cells, XP1, XPAC

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Pan Y.R., et al. (2009) Cell Cycle 8:655-664.;;James, et al. (2005) Andrews Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human XPA (1-273aa) purified from E. coli

Applications :

ELISA,WB,ICC/IF

IF Comment And Pic :

ICC/IF analysis of XPA in HaLa cells. The cell was stained with ATGA0502 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human XPA antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;; Lane 1.: SW480 cell lysate ;;Lane 2.: K562 cell lysate ;;Lane 3.: MCF7 cell lysate ;;Lane 4.: LNCaP cell lysate;; Lane 5.: Raji cell lysate

Reacts With :

Human

Clone Number :

AT71H3

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

P23025

Internal Search Terms :

XPA,ATGA0502-10ug,ATGA0502-20ug,ATGA0502-50ug,ATGA0502-100ug,ATGA0502-250ug,ATGA0502-500ug,ATGA0502-1mg,ATGA0502-10,ATGA0502-20,ATGA0502-50,ATGA0502-100,ATGA0502-250,ATGA0502-500,ATGA0502-1

more info or order :

NKMAX product webpage