Human CD94/KLRD1 antibody | NKMAX ATGA0487 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human CD94/KLRD1 antibody

catalog :

ATGA0487

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT13E3

reactivity :

human

application :

western blot, ELISA, FACS

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human CD94/KLRD1 antibody

Catalog number (SKU) :

ATGA0487

NCBI :

NP_002253

Description :

CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D, member 1 (KLRD1) is a human gene. The protein encoded by CD94 gene is a lectin, cluster of differentiation and a receptor that is involved in cell signaling and is expressed on the surface of natural killer cells in the innate immune system. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA) -E on target cells.

Alternative Names :

Killer cell lectin like receptor D1, Natural killer cells antigen CD94, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Cheent KS., et al. (2013) pnas. 110(42): 16981-16986.;; Shum BP., et al. (2008) Nat Immunol. 168(1): 240-252.;; Fang M., et al. (2011) Immunity 34(4): 579-589.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human KLRD1 (32-179aa) purified from E. coli

Applications :

ELISA, WB, FACS

WB Comment and Pic :

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human KLRD1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;;Lane 1.: K562 cell lysate ;;Lane 2.: MCF7 cell lysate ;;Lane 3.: A549 cell lysate The NK-92 cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human KLRD1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. {ATGA0487-WB2.jpg}

Reacts With :

Human

Clone Number :

AT13E3

Ab Usage :

The antibody has been tested by ELISA, Western blot analysis and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

FACS Comment and Pic :

Flow cytometry analysis of KLRD1 in PBMC cells. The cell was stained with ATGA0487 at 2-5ug for 1x106cells (red). A Goat anti mouse IgG (Alexa fluor 488) was used as the secondary antibody. Mouse monoclonal IgG was used as the isotype control (dark gray), cells without incubation with primary and secondary antibody was used as the negative control (light gray).

Antigen Species :

Human

Gene Category :

Immunology

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q13241

Internal Search Terms :

CD94,ATGA0487-10ug,ATGA0487-20ug,ATGA0487-50ug,ATGA0487-100ug,ATGA0487-250ug,ATGA0487-500ug,ATGA0487-1mg,ATGA0487-10,ATGA0487-20,ATGA0487-50,ATGA0487-100,ATGA0487-250,ATGA0487-500,ATGA0487-1

more info or order :

NKMAX product webpage