Human SSU72 antibody | NKMAX ATGA0470 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human SSU72 antibody

catalog :

ATGA0470

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT45E2

reactivity :

human

application :

western blot, ELISA

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human SSU72 antibody

Catalog number (SKU) :

ATGA0470

NCBI :

NP_054907

Description :

SSU72 RNA polymerase II CTD phosphatase homolog, also known as SSU72, is a highly conserved homologue of yeast Ssu72, a CTD phosphatase and a component of the polyadenylation/ termination machinery. Existing as multiple alternatively spliced isoforms, SSU72 interacts with TFIIB, Rb and DNAM-1 and functions to catalyze the dephosphorylation of target proteins, possibly playing a role in RNA processing and termination via dephosphorylation of Pol II.

Alternative Names :

SSu72 RNA polymerase II CTD phosphatase homolog, HSPC182, PNAS-120

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Dichtl B., et al. (2002) Mol Cell. 10: 1139-1150.;; Krishnamurthy S., et al. (2004) Mol Cell. 14: 387-394.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human SSU72 (1-194aa) purified from E. coli

Applications :

ELISA,WB

WB Comment and Pic :

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SSU72 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;;Lane 1.: Jurkat cell lysate;;Lane 2.: K562 cell lysate;;Lane 3.: HeLa cell lysate;;Lane 4.: MCF7 cell lysate;;Lane 5.: LnCap cell lysate

Reacts With :

Human

Clone Number :

AT45E2

Ab Usage :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q9NP77

Internal Search Terms :

SSU72,ATGA0470-10ug,ATGA0470-20ug,ATGA0470-50ug,ATGA0470-100ug,ATGA0470-250ug,ATGA0470-500ug,ATGA0470-1mg,ATGA0470-10,ATGA0470-20,ATGA0470-50,ATGA0470-100,ATGA0470-250,ATGA0470-500,ATGA0470-1

more info or order :

NKMAX product webpage