Human TIP30/HTATIP2 antibody | NKMAX ATGA0444 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human TIP30/HTATIP2 antibody

catalog :

ATGA0444

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT5D6

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human TIP30/HTATIP2 antibody

Catalog number (SKU) :

ATGA0444

NCBI :

AAH15358

Description :

HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy.

Alternative Names :

Oxidoreductase HTATP2, CC3, TIP30, SDR44u1, Oxidoreductase HTATP2, HTATIP 2, HTATIP-2, CC-3, TIP 30, TIP-30

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Shtivelman E., et al. (1997) Oncogene. 14(18): 2167-73. ;; Xiao H., et al. (1998) Proc Natl Acad Sci u S A. 95(5): 2146-2151.

Abs Host :

Mouse

Isotype :

IgG2a kappa

Immunogen :

Recombinant human HTATIP2 (1-242aa) purified from E. coli

Applications :

ELISA, WB, ICC/IF

IF Comment And Pic :

ICC/IF analysis of HTATIP2 in A549 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human HTATIP2 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green). ICC/IF analysis of HTATIP2 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human HTATIP2 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green). {ATGA0444-IF2.jpg}

WB Comment and Pic :

The cell lysate (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human HTATIP2 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;;Lane 1 : HeLa cell lysate

Reacts With :

Human

Clone Number :

AT5D6

Ab Usage :

The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Apoptosis

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q9BUP3

Internal Search Terms :

TIP-30, TIP30, TIP 30, SDR44u1, Oxidoreductase HTATP2, HTATIP-2, HTATIP2, HTATIP 2, CC-3, CC3, CC 3, ATGA0444-10ug, ATGA0444-20ug, ATGA0444-50ug, ATGA0444-100ug, ATGA0444-250ug, ATGA0444-500ug, ATGA0444-1mg, ATGA0444-010, ATGA0444-020, ATGA0444-050, ATGA0444-100, ATGA0444-250, ATGA0444-500, ATGA0444-01M

more info or order :

NKMAX product webpage